Targeting CX3CR1 Signaling Dynamics: A Critical Determinant in the Temporal Regulation of Post-Stroke Neurorepair

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Targeting CX3CR1 Signaling Dynamics: A Critical Determinant in the Temporal Regulation of Post-Stroke Neurorepair

Ischemic stroke ranks among the top global causes of disability and mortality, with a highly dynamic pathological process. Post-stroke neuroinflammation, mediated by microglia, demonstrates a dual role in both injury and repair. The CX3CR1/CX3CL1 signaling axis, highly expressed in microglia, acts a...

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Bibliographic Details
Main Authors:	Quan He, Tong Zhou, Quanwei He
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Series:	Brain Sciences
Subjects:	CX3CR1 ischemic stroke CX3CL1/CX3CR1 axis CX3CL1 microglia neurorepair
Online Access:	https://www.mdpi.com/2076-3425/15/7/759
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