Comparative analysis of protein kinases and associated domains between Ascomycota and Basidiomycota
Protein kinases play an important role in every aspect of cellular life. In this study, we systemically identified protein kinases from the predicted proteomes of 59 representative fungi from Ascomycota and Basidiomycota. Comparative analysis revealed that fungi from Ascomycota and Basidiomycota dif...
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| Language: | English |
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KeAi Communications Co., Ltd.
2019-01-01
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| Series: | Journal of Integrative Agriculture |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2095311918620222 |
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| author | Guo-liang PEI Jun GUO Qin-hu WANG Zhen-sheng KANG |
| author_facet | Guo-liang PEI Jun GUO Qin-hu WANG Zhen-sheng KANG |
| author_sort | Guo-liang PEI |
| collection | DOAJ |
| description | Protein kinases play an important role in every aspect of cellular life. In this study, we systemically identified protein kinases from the predicted proteomes of 59 representative fungi from Ascomycota and Basidiomycota. Comparative analysis revealed that fungi from Ascomycota and Basidiomycota differed in the number and variety of protein kinases. Some groups of protein kinases, such as calmodulin/calcium regulated kinases (CMGC) and those with the highest group percentages are the most prevalent protein kinases among all fungal species tested. In contrast, the STE group (homologs of the yeast STE7, STE11 and STE20 genes), was more abundant in Basidiomycetes than in Ascomycetes. Importantly, the distribution of some protein kinase families appeared to be subphylum-specific. The tyrosine kinase-like (TKL) group had a higher protein kinase density in Agaricomycotina fungi. In addition, the distribution of accessory domains, which could have functional implications, demonstrated that usage bias varied between the two phyla. Principal component analysis revealed a divergence between the main functional domains and associated domains in fungi. This study provides novel insights into the variety and expansion of fungal protein kinases between Ascomycota and Basidiomycota. |
| format | Article |
| id | doaj-art-6b7d8c5dcfc2422ba1a61d02aefcdbbf |
| institution | Matheson Library |
| issn | 2095-3119 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Journal of Integrative Agriculture |
| spelling | doaj-art-6b7d8c5dcfc2422ba1a61d02aefcdbbf2025-08-02T10:18:45ZengKeAi Communications Co., Ltd.Journal of Integrative Agriculture2095-31192019-01-0118196107Comparative analysis of protein kinases and associated domains between Ascomycota and BasidiomycotaGuo-liang PEI0Jun GUO1Qin-hu WANG2Zhen-sheng KANG3State Key Laboratory of Crop Stress Biology for Arid Areas, College of Plant Protection, Northwest A&F University, Yangling 712100, P.R.ChinaCorrespondence GUO Jun, Tel/Fax: +86-29-87082439; State Key Laboratory of Crop Stress Biology for Arid Areas, College of Plant Protection, Northwest A&F University, Yangling 712100, P.R.ChinaState Key Laboratory of Crop Stress Biology for Arid Areas, College of Plant Protection, Northwest A&F University, Yangling 712100, P.R.ChinaCorrespondence KANG Zhen-sheng, Tel/Fax: +86-29-87080061; State Key Laboratory of Crop Stress Biology for Arid Areas, College of Plant Protection, Northwest A&F University, Yangling 712100, P.R.ChinaProtein kinases play an important role in every aspect of cellular life. In this study, we systemically identified protein kinases from the predicted proteomes of 59 representative fungi from Ascomycota and Basidiomycota. Comparative analysis revealed that fungi from Ascomycota and Basidiomycota differed in the number and variety of protein kinases. Some groups of protein kinases, such as calmodulin/calcium regulated kinases (CMGC) and those with the highest group percentages are the most prevalent protein kinases among all fungal species tested. In contrast, the STE group (homologs of the yeast STE7, STE11 and STE20 genes), was more abundant in Basidiomycetes than in Ascomycetes. Importantly, the distribution of some protein kinase families appeared to be subphylum-specific. The tyrosine kinase-like (TKL) group had a higher protein kinase density in Agaricomycotina fungi. In addition, the distribution of accessory domains, which could have functional implications, demonstrated that usage bias varied between the two phyla. Principal component analysis revealed a divergence between the main functional domains and associated domains in fungi. This study provides novel insights into the variety and expansion of fungal protein kinases between Ascomycota and Basidiomycota.http://www.sciencedirect.com/science/article/pii/S2095311918620222protein kinasesassociated domainsAscomycotaBasidiomycota |
| spellingShingle | Guo-liang PEI Jun GUO Qin-hu WANG Zhen-sheng KANG Comparative analysis of protein kinases and associated domains between Ascomycota and Basidiomycota Journal of Integrative Agriculture protein kinases associated domains Ascomycota Basidiomycota |
| title | Comparative analysis of protein kinases and associated domains between Ascomycota and Basidiomycota |
| title_full | Comparative analysis of protein kinases and associated domains between Ascomycota and Basidiomycota |
| title_fullStr | Comparative analysis of protein kinases and associated domains between Ascomycota and Basidiomycota |
| title_full_unstemmed | Comparative analysis of protein kinases and associated domains between Ascomycota and Basidiomycota |
| title_short | Comparative analysis of protein kinases and associated domains between Ascomycota and Basidiomycota |
| title_sort | comparative analysis of protein kinases and associated domains between ascomycota and basidiomycota |
| topic | protein kinases associated domains Ascomycota Basidiomycota |
| url | http://www.sciencedirect.com/science/article/pii/S2095311918620222 |
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