Comparison of Carbapenem vs. Amikacin Antimicrobial Therapy for Pediatric Acute Pyelonephritis Caused by Extended-Spectrum Β-Lactamase-Positive Enterobacteriaceae

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Comparison of Carbapenem vs. Amikacin Antimicrobial Therapy for Pediatric Acute Pyelonephritis Caused by Extended-Spectrum Β-Lactamase-Positive Enterobacteriaceae

<b>Objectives</b>: Acute pyelonephritis (APN) caused by extended-spectrum β-lactamase (ESBL)-positive Enterobacteriaceae poses a growing therapeutic challenge in children, as carbapenems remain the mainstay of treatment even when susceptibility to alternative agents such as amikacin is d...

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Bibliographic Details
Main Authors:	Burcu Ceylan Cura Yayla, Tuğba Bedir Demirdağ, Anıl Tapısız, Yeşim Özdemir Atikel, Hasan Tezer, Elif Ayça Şahin, Kayhan Çağlar, Sevcan A. Bakkaloğlu, Necla Buyan
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Series:	Children
Subjects:	pediatric acute pyelonephritis extended-spectrum β-lactamase Enterobacteriaceae amikacin carbapenem
Online Access:	https://www.mdpi.com/2227-9067/12/7/945
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