Excretion of the drug glutaron - a new derivative of glutamic acid
In the study of excretion of the drug was found that glutaron determined in urine for at least 72 hours of the study. Renal clearance is 123 ml/hour, extrarenal - 34.84 ml/hour by intravenous route of administration. Superiority over extrarenal and renal clearance correlates with earlier data on the...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
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LLC “Publisher OKI”
2014-04-01
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| Series: | Фармакокинетика и Фармакодинамика |
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| Online Access: | https://www.pharmacokinetica.ru/jour/article/view/141 |
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| author | L. A. Smirnova E. A. Suchkov A. F. Ryabukha K. A. Kuznetsov I. N. Tyurenkov V. N. Perfilova |
| author_facet | L. A. Smirnova E. A. Suchkov A. F. Ryabukha K. A. Kuznetsov I. N. Tyurenkov V. N. Perfilova |
| author_sort | L. A. Smirnova |
| collection | DOAJ |
| description | In the study of excretion of the drug was found that glutaron determined in urine for at least 72 hours of the study. Renal clearance is 123 ml/hour, extrarenal - 34.84 ml/hour by intravenous route of administration. Superiority over extrarenal and renal clearance correlates with earlier data on the distribution of glutaron in organs and tissues. The drug was determined in the organs responsible for elimination (liver, kidneys and lungs) at high concentrations. |
| format | Article |
| id | doaj-art-6b5cb7bcb6094e1b82fd9f874c5554fe |
| institution | Matheson Library |
| issn | 2587-7836 2686-8830 |
| language | Russian |
| publishDate | 2014-04-01 |
| publisher | LLC “Publisher OKI” |
| record_format | Article |
| series | Фармакокинетика и Фармакодинамика |
| spelling | doaj-art-6b5cb7bcb6094e1b82fd9f874c5554fe2025-08-03T13:00:46ZrusLLC “Publisher OKI”Фармакокинетика и Фармакодинамика2587-78362686-88302014-04-01015051140Excretion of the drug glutaron - a new derivative of glutamic acidL. A. Smirnova0E. A. Suchkov1A. F. Ryabukha2K. A. Kuznetsov3I. N. Tyurenkov4V. N. Perfilova5Volgograd Medical UniversityVolgograd Medical UniversityVolgograd Medical UniversityVolgograd Medical UniversityVolgograd Medical UniversityVolgograd Medical UniversityIn the study of excretion of the drug was found that glutaron determined in urine for at least 72 hours of the study. Renal clearance is 123 ml/hour, extrarenal - 34.84 ml/hour by intravenous route of administration. Superiority over extrarenal and renal clearance correlates with earlier data on the distribution of glutaron in organs and tissues. The drug was determined in the organs responsible for elimination (liver, kidneys and lungs) at high concentrations.https://www.pharmacokinetica.ru/jour/article/view/141производные глутаминовой кислотыэкскрецияderivatives of glutamic acidexcretion |
| spellingShingle | L. A. Smirnova E. A. Suchkov A. F. Ryabukha K. A. Kuznetsov I. N. Tyurenkov V. N. Perfilova Excretion of the drug glutaron - a new derivative of glutamic acid Фармакокинетика и Фармакодинамика производные глутаминовой кислоты экскреция derivatives of glutamic acid excretion |
| title | Excretion of the drug glutaron - a new derivative of glutamic acid |
| title_full | Excretion of the drug glutaron - a new derivative of glutamic acid |
| title_fullStr | Excretion of the drug glutaron - a new derivative of glutamic acid |
| title_full_unstemmed | Excretion of the drug glutaron - a new derivative of glutamic acid |
| title_short | Excretion of the drug glutaron - a new derivative of glutamic acid |
| title_sort | excretion of the drug glutaron a new derivative of glutamic acid |
| topic | производные глутаминовой кислоты экскреция derivatives of glutamic acid excretion |
| url | https://www.pharmacokinetica.ru/jour/article/view/141 |
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