Myocardial infarction: risk factors and preventive measures in nuclear industry workers
Aim. To assess the associations between radiation exposure and the risk of acute myocardial infarction (AMI) in nuclear industry workers; to identify the risk factors (RFs) of MI; to suggest relevant preventive measures in this organised population. Material and methods. This ongoing prospective pop...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2011-02-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1458 |
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| author | Yu. V. Semenova R. M. Takhauov A. B. Karpov T. M. Litvinenko D. E. Kalinkin |
| author_facet | Yu. V. Semenova R. M. Takhauov A. B. Karpov T. M. Litvinenko D. E. Kalinkin |
| author_sort | Yu. V. Semenova |
| collection | DOAJ |
| description | Aim. To assess the associations between radiation exposure and the risk of acute myocardial infarction (AMI) in nuclear industry workers; to identify the risk factors (RFs) of MI; to suggest relevant preventive measures in this organised population. Material and methods. This ongoing prospective population-based study started in 1998. Over 2001-2006, AMI was diagnosed in 1665 patients, including 439 cases with previous radiation exposure. The case-control analysis included randomly selected AMI cases in 380 workers of the Siberian Chemical Complex (263 and 117 people involved in the main and auxiliary production processes, respectively) and in-hospital controls. For every participant, 65 parameters were registered, including socioeconomic characteristics, RFs, co-morbidities, biochemical parameters (such as total cholesterol), main clinical data, and the total radiation dose.Results. In nuclear industry workers with traditional RFs of AMI, the important risk determinant was not the total radiation dose, but the individual features of radiation dose accumulation. Conclusion. To improve the effectiveness of AMI morbidity and mortality prevention in this organised population, the risk groups should be defined on the basis of the most important RFs. For nuclear industry workers, these RFs include not only traditional risk predictors (arterial hypertension, smoking, hypercholesterolemia, diabetes mellitus), but also the individual features of radiation dose accumulation (age of initial radiation exposure, exposure duration). |
| format | Article |
| id | doaj-art-6b25afc3365d4a068a183c1e58ee3cc0 |
| institution | Matheson Library |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2011-02-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-6b25afc3365d4a068a183c1e58ee3cc02025-08-04T12:50:16Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252011-02-0110123291168Myocardial infarction: risk factors and preventive measures in nuclear industry workersYu. V. Semenova0R. M. Takhauov1A. B. Karpov2T. M. Litvinenko3D. E. Kalinkin4Seversk Biophysics Research Centre; Clinical Hospital No. 81Seversk Biophysics Research Centre; Research Laboratory “Radiation Medicine and Radiobiology”, Siberian Branch, Russian Academy of Medical SciencesSeversk Biophysics Research Centre; Research Laboratory “Radiation Medicine and Radiobiology”, Siberian Branch, Russian Academy of Medical SciencesSeversk Biophysics Research Centre; Clinical Hospital No. 81Seversk Biophysics Research Centre; Research Laboratory “Radiation Medicine and Radiobiology”, Siberian Branch, Russian Academy of Medical SciencesAim. To assess the associations between radiation exposure and the risk of acute myocardial infarction (AMI) in nuclear industry workers; to identify the risk factors (RFs) of MI; to suggest relevant preventive measures in this organised population. Material and methods. This ongoing prospective population-based study started in 1998. Over 2001-2006, AMI was diagnosed in 1665 patients, including 439 cases with previous radiation exposure. The case-control analysis included randomly selected AMI cases in 380 workers of the Siberian Chemical Complex (263 and 117 people involved in the main and auxiliary production processes, respectively) and in-hospital controls. For every participant, 65 parameters were registered, including socioeconomic characteristics, RFs, co-morbidities, biochemical parameters (such as total cholesterol), main clinical data, and the total radiation dose.Results. In nuclear industry workers with traditional RFs of AMI, the important risk determinant was not the total radiation dose, but the individual features of radiation dose accumulation. Conclusion. To improve the effectiveness of AMI morbidity and mortality prevention in this organised population, the risk groups should be defined on the basis of the most important RFs. For nuclear industry workers, these RFs include not only traditional risk predictors (arterial hypertension, smoking, hypercholesterolemia, diabetes mellitus), but also the individual features of radiation dose accumulation (age of initial radiation exposure, exposure duration).https://cardiovascular.elpub.ru/jour/article/view/1458acute myocardial infarctionrisk factors“low” radiation doses |
| spellingShingle | Yu. V. Semenova R. M. Takhauov A. B. Karpov T. M. Litvinenko D. E. Kalinkin Myocardial infarction: risk factors and preventive measures in nuclear industry workers Кардиоваскулярная терапия и профилактика acute myocardial infarction risk factors “low” radiation doses |
| title | Myocardial infarction: risk factors and preventive measures in nuclear industry workers |
| title_full | Myocardial infarction: risk factors and preventive measures in nuclear industry workers |
| title_fullStr | Myocardial infarction: risk factors and preventive measures in nuclear industry workers |
| title_full_unstemmed | Myocardial infarction: risk factors and preventive measures in nuclear industry workers |
| title_short | Myocardial infarction: risk factors and preventive measures in nuclear industry workers |
| title_sort | myocardial infarction risk factors and preventive measures in nuclear industry workers |
| topic | acute myocardial infarction risk factors “low” radiation doses |
| url | https://cardiovascular.elpub.ru/jour/article/view/1458 |
| work_keys_str_mv | AT yuvsemenova myocardialinfarctionriskfactorsandpreventivemeasuresinnuclearindustryworkers AT rmtakhauov myocardialinfarctionriskfactorsandpreventivemeasuresinnuclearindustryworkers AT abkarpov myocardialinfarctionriskfactorsandpreventivemeasuresinnuclearindustryworkers AT tmlitvinenko myocardialinfarctionriskfactorsandpreventivemeasuresinnuclearindustryworkers AT dekalinkin myocardialinfarctionriskfactorsandpreventivemeasuresinnuclearindustryworkers |