ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW)
In this review article, we present current clinical data about the effects of transfused hemocomponents upon immune system of the recipients, and about transfusion-related immunomodulation, with emphasis on the role of T-regulatory (Treg) cells in these events. The article describes a role of Treg’s...
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Format: | Article |
Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-11-01
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Series: | Медицинская иммунология |
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Online Access: | https://www.mimmun.ru/mimmun/article/view/726 |
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author | T. V. Glazanova O. E. Rozanova L. N. Bubnova |
author_facet | T. V. Glazanova O. E. Rozanova L. N. Bubnova |
author_sort | T. V. Glazanova |
collection | DOAJ |
description | In this review article, we present current clinical data about the effects of transfused hemocomponents upon immune system of the recipients, and about transfusion-related immunomodulation, with emphasis on the role of T-regulatory (Treg) cells in these events. The article describes a role of Treg’s in development of tolerance to self-antigens, in decrease of anti-neoplastic and anti-infection immune response, and their proposed role in transfusion-related immunomodulatory effects. |
format | Article |
id | doaj-art-6b0a69f7ab6b45f889ac26d3d3fab59c |
institution | Matheson Library |
issn | 1563-0625 2313-741X |
language | Russian |
publishDate | 2014-11-01 |
publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
record_format | Article |
series | Медицинская иммунология |
spelling | doaj-art-6b0a69f7ab6b45f889ac26d3d3fab59c2025-08-04T14:30:33ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-11-0116540941610.15789/1563-0625-2014-5-409-416706ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW)T. V. Glazanova0O. E. Rozanova1L. N. Bubnova2Russian Research Institute of Hematology and Transfusiology, Russian Medical and Biological Agency, St. Petersburg, Russian FederationRussian Research Institute of Hematology and Transfusiology, Russian Medical and Biological Agency, St. Petersburg, Russian FederationRussian Research Institute of Hematology and Transfusiology, Russian Medical and Biological Agency, St. Petersburg, Russian FederationIn this review article, we present current clinical data about the effects of transfused hemocomponents upon immune system of the recipients, and about transfusion-related immunomodulation, with emphasis on the role of T-regulatory (Treg) cells in these events. The article describes a role of Treg’s in development of tolerance to self-antigens, in decrease of anti-neoplastic and anti-infection immune response, and their proposed role in transfusion-related immunomodulatory effects.https://www.mimmun.ru/mimmun/article/view/726blood componentstransfusionsimmunityт regulatory cellsimmune modulation |
spellingShingle | T. V. Glazanova O. E. Rozanova L. N. Bubnova ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW) Медицинская иммунология blood components transfusions immunity т regulatory cells immune modulation |
title | ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW) |
title_full | ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW) |
title_fullStr | ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW) |
title_full_unstemmed | ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW) |
title_short | ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW) |
title_sort | role of t regulatory cells тreg in transfusion associated immunomodulation review |
topic | blood components transfusions immunity т regulatory cells immune modulation |
url | https://www.mimmun.ru/mimmun/article/view/726 |
work_keys_str_mv | AT tvglazanova roleoftregulatorycellstregintransfusionassociatedimmunomodulationreview AT oerozanova roleoftregulatorycellstregintransfusionassociatedimmunomodulationreview AT lnbubnova roleoftregulatorycellstregintransfusionassociatedimmunomodulationreview |