ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW)

In this review article, we present current clinical data about the effects of transfused hemocomponents upon immune system of the recipients, and about transfusion-related immunomodulation, with emphasis on the role of T-regulatory (Treg) cells in these events. The article describes a role of Treg’s...

Full description

Saved in:
Bibliographic Details
Main Authors: T. V. Glazanova, O. E. Rozanova, L. N. Bubnova
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-11-01
Series:Медицинская иммунология
Subjects:
Online Access:https://www.mimmun.ru/mimmun/article/view/726
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1839571544110530560
author T. V. Glazanova
O. E. Rozanova
L. N. Bubnova
author_facet T. V. Glazanova
O. E. Rozanova
L. N. Bubnova
author_sort T. V. Glazanova
collection DOAJ
description In this review article, we present current clinical data about the effects of transfused hemocomponents upon immune system of the recipients, and about transfusion-related immunomodulation, with emphasis on the role of T-regulatory (Treg) cells in these events. The article describes a role of Treg’s in development of tolerance to self-antigens, in decrease of anti-neoplastic and anti-infection immune response, and their proposed role in transfusion-related immunomodulatory effects.
format Article
id doaj-art-6b0a69f7ab6b45f889ac26d3d3fab59c
institution Matheson Library
issn 1563-0625
2313-741X
language Russian
publishDate 2014-11-01
publisher St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
record_format Article
series Медицинская иммунология
spelling doaj-art-6b0a69f7ab6b45f889ac26d3d3fab59c2025-08-04T14:30:33ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-11-0116540941610.15789/1563-0625-2014-5-409-416706ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW)T. V. Glazanova0O. E. Rozanova1L. N. Bubnova2Russian Research Institute of Hematology and Transfusiology, Russian Medical and Biological Agency, St. Petersburg, Russian FederationRussian Research Institute of Hematology and Transfusiology, Russian Medical and Biological Agency, St. Petersburg, Russian FederationRussian Research Institute of Hematology and Transfusiology, Russian Medical and Biological Agency, St. Petersburg, Russian FederationIn this review article, we present current clinical data about the effects of transfused hemocomponents upon immune system of the recipients, and about transfusion-related immunomodulation, with emphasis on the role of T-regulatory (Treg) cells in these events. The article describes a role of Treg’s in development of tolerance to self-antigens, in decrease of anti-neoplastic and anti-infection immune response, and their proposed role in transfusion-related immunomodulatory effects.https://www.mimmun.ru/mimmun/article/view/726blood componentstransfusionsimmunityт regulatory cellsimmune modulation
spellingShingle T. V. Glazanova
O. E. Rozanova
L. N. Bubnova
ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW)
Медицинская иммунология
blood components
transfusions
immunity
т regulatory cells
immune modulation
title ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW)
title_full ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW)
title_fullStr ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW)
title_full_unstemmed ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW)
title_short ROLE OF T REGULATORY CELLS (Тreg) IN TRANSFUSION-ASSOCIATED IMMUNOMODULATION (REVIEW)
title_sort role of t regulatory cells тreg in transfusion associated immunomodulation review
topic blood components
transfusions
immunity
т regulatory cells
immune modulation
url https://www.mimmun.ru/mimmun/article/view/726
work_keys_str_mv AT tvglazanova roleoftregulatorycellstregintransfusionassociatedimmunomodulationreview
AT oerozanova roleoftregulatorycellstregintransfusionassociatedimmunomodulationreview
AT lnbubnova roleoftregulatorycellstregintransfusionassociatedimmunomodulationreview