Investigating the link between APCI1307K mutation and breast cancer in a Jordanian Arab population

Investigating the link between APCI1307K mutation and breast cancer in a Jordanian Arab population

IntroductionAPCI1307K missense mutation, welldescribed in Ashkenazi Jewish, is commonly encountered among Jordanian patients with solid tumors. In this study, we investigated the potential association between the APC gene (I1307K variant) and the risk of breast cancer among Jordanian Arab patients.M...

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Bibliographic Details
Main Authors: Baha Sharaf, Hira Bani Hani, Anas Zayed, Maha Barbar, Suhaib Khater, Ahmad Hushki, Rashid Abdel-Razeq, Mohammad Titi, Reem Al-Halalsheh, Suleiman Mahafdah, Lin Ashour, Hikmat Abdel-Razeq
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oncology
Subjects:
APCI1307K
breast cancer
colon cancer
APC
germline genetic testing
hereditary cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1557341/full
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