Cytotoxic effect of the VVGMCSF-Lact oncolytic virus against 3D cultures of human glioblastoma cells U-87 MG

Cytotoxic effect of the VVGMCSF-Lact oncolytic virus against 3D cultures of human glioblastoma cells U-87 MG

Background. One of the promising methods of treating tumors is virotherapy, which is based on direct lysis of cancer cells by a virus and a virus-mediated antitumor immune response of the body. For the recombinant vaccinia virus strain VVGMCSF-Lact, producing human GMCSF and the oncotoxic protein la...

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Bibliographic Details
Main Authors: M. A. Dymova, T. A. Shnaider, S. A. Chechetkina, G. O. Petrov, D. O. Malysheva, D. V. Drokov, A. B. Ageenko, N. S. Vasileva, V. A. Richter, E. V. Kuligina
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2024-01-01
Series:Acta Biomedica Scientifica
Subjects:
glioblastoma
neurospheres
oncolytic virus
vv-gmcsf-lact
Online Access:https://www.actabiomedica.ru/jour/article/view/4502
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