Effect of triftazin (trifluoperazine) on the symptoms of autism spectrum disorders in rats with fetal valproatate syndrome
The effect of triftazin (trifluoperazine) on social interaction abnormalities as a main feature of autism spectrum disorders, exploratory behavior and learning capacity was studied in rats with fetal valproatate syndrome. It was shown that triftazin at a dose of 0,35 mg/kg does not affect the defici...
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Main Authors: | , , , |
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Format: | Article |
Language: | Russian |
Published: |
LLC “Publisher OKI”
2017-07-01
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Series: | Фармакокинетика и Фармакодинамика |
Subjects: | |
Online Access: | https://www.pharmacokinetica.ru/jour/article/view/25 |
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Summary: | The effect of triftazin (trifluoperazine) on social interaction abnormalities as a main feature of autism spectrum disorders, exploratory behavior and learning capacity was studied in rats with fetal valproatate syndrome. It was shown that triftazin at a dose of 0,35 mg/kg does not affect the deficit of social interaction, spatial learning or memory but improves exploratory activity by decreasing anxiety in rats with fetal valproate syndrome. |
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ISSN: | 2587-7836 2686-8830 |