Radiolabeling of porcine, murine growth hormone and a potential antagonist G118R-mGH for biodistribution study

Radiolabeling of porcine, murine growth hormone and a potential antagonist G118R-mGH for biodistribution study

This study aimed to radiolabel porcine growth hormone (pGH), murine growth hormone (mGH), and its antagonist (G118R-mGH) with the iodine radioisotopes ¹³¹I and ¹²³I, to investigate the biodistribution and brain transport of these hormones. Radiolabeling was performed using the Chloramine T method,...

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Bibliographic Details
Main Authors: Amanda Palermo Nunes, Filipe Menezes, Larissa Andrade Almeida, Stephanie A. Pomin, Patricia Lima Falcão, Carlos Soares
Format: Article
Language:English
Published: Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) 2025-05-01
Series:Brazilian Journal of Radiation Sciences
Subjects:
Growth Hormone
Radiolabeling
Iodine
SPECT-CT
Online Access:https://bjrs.org.br/revista/index.php/REVISTA/article/view/2744
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