A case report of primary breast angiosarcoma: An uncommon malignancy
Angiosarcoma of the breast is a rare and aggressive form of cancer that originates from vascular or lymphatic tissues, representing only 0.04% of malignant breast lesions. Variance in the clinical, pathological, and radiological presentations often leads to challenges in diagnosis. We present a case...
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| Language: | English |
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Elsevier
2025-09-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325004789 |
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| author | Ayesha Afzal, MBBS, FCPS Muhammad Junaid Tahir, MBBS Asma Asghar, MBBS FCPS Hira Yaqub, MBBS Anis Ur Rehman, MBBS, FRCR Aamer Iftikhar, MBBS, FRCR |
| author_facet | Ayesha Afzal, MBBS, FCPS Muhammad Junaid Tahir, MBBS Asma Asghar, MBBS FCPS Hira Yaqub, MBBS Anis Ur Rehman, MBBS, FRCR Aamer Iftikhar, MBBS, FRCR |
| author_sort | Ayesha Afzal, MBBS, FCPS |
| collection | DOAJ |
| description | Angiosarcoma of the breast is a rare and aggressive form of cancer that originates from vascular or lymphatic tissues, representing only 0.04% of malignant breast lesions. Variance in the clinical, pathological, and radiological presentations often leads to challenges in diagnosis. We present a case of a 32-year-old lactating female having a painless swelling in her right breast for 6 months, with a significant increase in size in 1 month. Clinical assessment indicated the presence of a mass at the superior edge of the areola, with associated bluish skin discoloration. Ultrasonography revealed a vascular lesion characterized by mixed echogenicity. A core biopsy confirmed the diagnosis of angiosarcoma. Imaging studies, including computed tomography (CT) and bone scans, ruled out distant metastases. Subsequently, surgical excision was performed, and histopathological analysis reaffirmed the diagnosis of angiosarcoma. Radiotherapy was deemed unsuitable due to the potential risk of recurrence or radiation-induced secondary angiosarcoma. This case highlights the necessity of a multidisciplinary approach in optimizing diagnosis and treatment, with surgical excision playing a pivotal role in disease management. |
| format | Article |
| id | doaj-art-680e38adb5014e5087c1e14821b461a5 |
| institution | Matheson Library |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-680e38adb5014e5087c1e14821b461a52025-07-13T04:53:52ZengElsevierRadiology Case Reports1930-04332025-09-0120943254330A case report of primary breast angiosarcoma: An uncommon malignancyAyesha Afzal, MBBS, FCPS0Muhammad Junaid Tahir, MBBS1Asma Asghar, MBBS FCPS2Hira Yaqub, MBBS3Anis Ur Rehman, MBBS, FRCR4Aamer Iftikhar, MBBS, FRCR5Department of Radiology, Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore, PakistanDepartment of Radiology, Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore, Pakistan; Corresponding author.Department of Radiology, Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore, PakistanDepartment of Pathology, Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore, PakistanDepartment of Radiology, Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore, PakistanDepartment of Radiology, Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore, PakistanAngiosarcoma of the breast is a rare and aggressive form of cancer that originates from vascular or lymphatic tissues, representing only 0.04% of malignant breast lesions. Variance in the clinical, pathological, and radiological presentations often leads to challenges in diagnosis. We present a case of a 32-year-old lactating female having a painless swelling in her right breast for 6 months, with a significant increase in size in 1 month. Clinical assessment indicated the presence of a mass at the superior edge of the areola, with associated bluish skin discoloration. Ultrasonography revealed a vascular lesion characterized by mixed echogenicity. A core biopsy confirmed the diagnosis of angiosarcoma. Imaging studies, including computed tomography (CT) and bone scans, ruled out distant metastases. Subsequently, surgical excision was performed, and histopathological analysis reaffirmed the diagnosis of angiosarcoma. Radiotherapy was deemed unsuitable due to the potential risk of recurrence or radiation-induced secondary angiosarcoma. This case highlights the necessity of a multidisciplinary approach in optimizing diagnosis and treatment, with surgical excision playing a pivotal role in disease management.http://www.sciencedirect.com/science/article/pii/S1930043325004789Primary angiosarcomaUltrasoundVascularTumor markersAtypical endothelial cells |
| spellingShingle | Ayesha Afzal, MBBS, FCPS Muhammad Junaid Tahir, MBBS Asma Asghar, MBBS FCPS Hira Yaqub, MBBS Anis Ur Rehman, MBBS, FRCR Aamer Iftikhar, MBBS, FRCR A case report of primary breast angiosarcoma: An uncommon malignancy Radiology Case Reports Primary angiosarcoma Ultrasound Vascular Tumor markers Atypical endothelial cells |
| title | A case report of primary breast angiosarcoma: An uncommon malignancy |
| title_full | A case report of primary breast angiosarcoma: An uncommon malignancy |
| title_fullStr | A case report of primary breast angiosarcoma: An uncommon malignancy |
| title_full_unstemmed | A case report of primary breast angiosarcoma: An uncommon malignancy |
| title_short | A case report of primary breast angiosarcoma: An uncommon malignancy |
| title_sort | case report of primary breast angiosarcoma an uncommon malignancy |
| topic | Primary angiosarcoma Ultrasound Vascular Tumor markers Atypical endothelial cells |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325004789 |
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