INNOVATIVE TECHNOLOGIES IN THE IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS IN CONTACTS OF THE CENTERS OF TUBERCULOSIS INFECTION
Purpose: comparative estimation of the efficacy of Mantoux test with 2 TE PPD-L, DiaskintestR, and QuantiFERONRTBGoldfor identification of active and latent tuberculosis infection at contact persons.Materials and Мethods: the study included 220 people from tuberculosis infection foci. All contact pe...
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State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation
2015-09-01
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| Series: | Медицинский вестник Юга России |
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| Online Access: | https://www.medicalherald.ru/jour/article/view/297 |
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| author | L. A. Shovkun I. M. Franchuk Ye. D. Kampos A. V. Konstantinova O. V. Ilyina |
| author_facet | L. A. Shovkun I. M. Franchuk Ye. D. Kampos A. V. Konstantinova O. V. Ilyina |
| author_sort | L. A. Shovkun |
| collection | DOAJ |
| description | Purpose: comparative estimation of the efficacy of Mantoux test with 2 TE PPD-L, DiaskintestR, and QuantiFERONRTBGoldfor identification of active and latent tuberculosis infection at contact persons.Materials and Мethods: the study included 220 people from tuberculosis infection foci. All contact persons underwent the Mantoux test with 2 TE PPD-L and the DiaskintestR. The in vitro QuantiFERONRTBGold test was done before the intracutaneous probes. The statistical manipulation of the obtained data was performed using the Statistica 6.0 package under Windows XP.Results: the Mantoux test with 2 TE PPD-L was reliably not distinguished for persons with active tuberculosis, residual posttuberculosis changes, and latent tuberculosis infections. DiaskintestR and QuantiFERONRTBGold possessed statistically significant differences depending on the investigated group.Summary: the Mantoux test with 2 TE PPD-L has low sensitivity and specificity, and not effective enough to detect active and latent tuberculosis infection. The usage of DiaskintestR and QuantiFERONRTBGold allows to detect and identify tuberculosis infection both active and latent. |
| format | Article |
| id | doaj-art-67594e6bc02c4f11b22a1657f9d5caec |
| institution | Matheson Library |
| issn | 2219-8075 2618-7876 |
| language | English |
| publishDate | 2015-09-01 |
| publisher | State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation |
| record_format | Article |
| series | Медицинский вестник Юга России |
| spelling | doaj-art-67594e6bc02c4f11b22a1657f9d5caec2025-07-03T16:13:37ZengState Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian FederationМедицинский вестник Юга России2219-80752618-78762015-09-010311611910.21886/2219-8075-2015-3-116-119296INNOVATIVE TECHNOLOGIES IN THE IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS IN CONTACTS OF THE CENTERS OF TUBERCULOSIS INFECTIONL. A. Shovkun0I. M. Franchuk1Ye. D. Kampos2A. V. Konstantinova3O. V. Ilyina4Rostov State Medical UniversityRostov State Medical UniversityRostov State Medical UniversityRostov State Medical UniversityRostov State Medical UniversityPurpose: comparative estimation of the efficacy of Mantoux test with 2 TE PPD-L, DiaskintestR, and QuantiFERONRTBGoldfor identification of active and latent tuberculosis infection at contact persons.Materials and Мethods: the study included 220 people from tuberculosis infection foci. All contact persons underwent the Mantoux test with 2 TE PPD-L and the DiaskintestR. The in vitro QuantiFERONRTBGold test was done before the intracutaneous probes. The statistical manipulation of the obtained data was performed using the Statistica 6.0 package under Windows XP.Results: the Mantoux test with 2 TE PPD-L was reliably not distinguished for persons with active tuberculosis, residual posttuberculosis changes, and latent tuberculosis infections. DiaskintestR and QuantiFERONRTBGold possessed statistically significant differences depending on the investigated group.Summary: the Mantoux test with 2 TE PPD-L has low sensitivity and specificity, and not effective enough to detect active and latent tuberculosis infection. The usage of DiaskintestR and QuantiFERONRTBGold allows to detect and identify tuberculosis infection both active and latent.https://www.medicalherald.ru/jour/article/view/297tuberculosis, mantoux test 2 te ppd-l, diaskintes*, quantiferon*tbgold |
| spellingShingle | L. A. Shovkun I. M. Franchuk Ye. D. Kampos A. V. Konstantinova O. V. Ilyina INNOVATIVE TECHNOLOGIES IN THE IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS IN CONTACTS OF THE CENTERS OF TUBERCULOSIS INFECTION Медицинский вестник Юга России tuberculosis, mantoux test 2 te ppd-l, diaskintes*, quantiferon*tbgold |
| title | INNOVATIVE TECHNOLOGIES IN THE IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS IN CONTACTS OF THE CENTERS OF TUBERCULOSIS INFECTION |
| title_full | INNOVATIVE TECHNOLOGIES IN THE IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS IN CONTACTS OF THE CENTERS OF TUBERCULOSIS INFECTION |
| title_fullStr | INNOVATIVE TECHNOLOGIES IN THE IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS IN CONTACTS OF THE CENTERS OF TUBERCULOSIS INFECTION |
| title_full_unstemmed | INNOVATIVE TECHNOLOGIES IN THE IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS IN CONTACTS OF THE CENTERS OF TUBERCULOSIS INFECTION |
| title_short | INNOVATIVE TECHNOLOGIES IN THE IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS IN CONTACTS OF THE CENTERS OF TUBERCULOSIS INFECTION |
| title_sort | innovative technologies in the immunological diagnosis of tuberculosis in contacts of the centers of tuberculosis infection |
| topic | tuberculosis, mantoux test 2 te ppd-l, diaskintes*, quantiferon*tbgold |
| url | https://www.medicalherald.ru/jour/article/view/297 |
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