Impact of inferior vena cava obstruction during orthotopic liver transplantation without venovenous bypass grafting on early postoperative renal function (pilot analysis)
Ligation of the inferior vena cava (IVC) during classical orthotopic liver transplantation (OLT) may be followed by pronounced hemodynamic changes and may provoke renal dysfunction. The authors have examined the impact of IVC ligation during OLT without venovenous bypass grafting on early postoperat...
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N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
2018-08-01
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| Series: | Трансплантология (Москва) |
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| Online Access: | https://www.jtransplantologiya.ru/jour/article/view/239 |
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| author | Ye. O. Santotsky A. F. Minov D. I. Yurlevich L. V. Kirkovsky S. V. Korotkov D. P. Kharkov L. S. Bolonkin Yu. V. Slobodin Ye. L. Avdei A. M. Fedoruk A. M. Dzyadzko A. Ye. Shcherba O. O. Rummo I. L. Kulinkovich P. V. Kozich |
| author_facet | Ye. O. Santotsky A. F. Minov D. I. Yurlevich L. V. Kirkovsky S. V. Korotkov D. P. Kharkov L. S. Bolonkin Yu. V. Slobodin Ye. L. Avdei A. M. Fedoruk A. M. Dzyadzko A. Ye. Shcherba O. O. Rummo I. L. Kulinkovich P. V. Kozich |
| author_sort | Ye. O. Santotsky |
| collection | DOAJ |
| description | Ligation of the inferior vena cava (IVC) during classical orthotopic liver transplantation (OLT) may be followed by pronounced hemodynamic changes and may provoke renal dysfunction. The authors have examined the impact of IVC ligation during OLT without venovenous bypass grafting on early postoperative renal function in 6 patients. The Cockcroft-Gault formula was used to evaluate renal function from the creatinine clearance on postoperative days 1, 3, 7, and 10. The endogenous creatinine clearance was diminished within the first 24 hours after surgery; this was 68.2±18.1 (24.3—146) ml/min and significantly correlated with that before OLT, with the mean blood pressure (BPmean) in the icteric period, and with age. At the same time, icteric BPmean was in the normal range — 77.2±1.59 (71.6—81.6) mm Hg and clinical renal failure developed in a female patient with significant preoperative renal dysfunction. Thus, IVC ligation at OLT with IVC interposition in the study contributed to a lower endogenous creatinine clearance within the first 24 postoperative hours, but results in no clinical renal function aggravation. |
| format | Article |
| id | doaj-art-660aaf2a6787499f85e72d2e7a6c1a08 |
| institution | Matheson Library |
| issn | 2074-0506 2542-0909 |
| language | English |
| publishDate | 2018-08-01 |
| publisher | N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department |
| record_format | Article |
| series | Трансплантология (Москва) |
| spelling | doaj-art-660aaf2a6787499f85e72d2e7a6c1a082025-08-04T10:31:16ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092018-08-0101434510.23873/2074-0506-2009-0-1-43-45228Impact of inferior vena cava obstruction during orthotopic liver transplantation without venovenous bypass grafting on early postoperative renal function (pilot analysis)Ye. O. Santotsky0A. F. Minov1D. I. Yurlevich2L. V. Kirkovsky3S. V. Korotkov4D. P. Kharkov5L. S. Bolonkin6Yu. V. Slobodin7Ye. L. Avdei8A. M. Fedoruk9A. M. Dzyadzko10A. Ye. Shcherba11O. O. Rummo12I. L. Kulinkovich13P. V. Kozich14City Clinical Hospital NineCity Clinical Hospital NineCity Clinical Hospital NineCity Clinical Hospital NineCity Clinical Hospital NineCity Clinical Hospital NineCity Clinical Hospital NineCity Clinical Hospital NineCity Clinical Hospital NineCity Clinical Hospital NineCity Clinical Hospital NineCity Clinical Hospital NineCity Clinical Hospital NineCity Clinical Hospital NineCity Clinical Hospital NineLigation of the inferior vena cava (IVC) during classical orthotopic liver transplantation (OLT) may be followed by pronounced hemodynamic changes and may provoke renal dysfunction. The authors have examined the impact of IVC ligation during OLT without venovenous bypass grafting on early postoperative renal function in 6 patients. The Cockcroft-Gault formula was used to evaluate renal function from the creatinine clearance on postoperative days 1, 3, 7, and 10. The endogenous creatinine clearance was diminished within the first 24 hours after surgery; this was 68.2±18.1 (24.3—146) ml/min and significantly correlated with that before OLT, with the mean blood pressure (BPmean) in the icteric period, and with age. At the same time, icteric BPmean was in the normal range — 77.2±1.59 (71.6—81.6) mm Hg and clinical renal failure developed in a female patient with significant preoperative renal dysfunction. Thus, IVC ligation at OLT with IVC interposition in the study contributed to a lower endogenous creatinine clearance within the first 24 postoperative hours, but results in no clinical renal function aggravation.https://www.jtransplantologiya.ru/jour/article/view/239liver transplantationinferior vena cava obstructionpostoperative complicationsacute renal failure |
| spellingShingle | Ye. O. Santotsky A. F. Minov D. I. Yurlevich L. V. Kirkovsky S. V. Korotkov D. P. Kharkov L. S. Bolonkin Yu. V. Slobodin Ye. L. Avdei A. M. Fedoruk A. M. Dzyadzko A. Ye. Shcherba O. O. Rummo I. L. Kulinkovich P. V. Kozich Impact of inferior vena cava obstruction during orthotopic liver transplantation without venovenous bypass grafting on early postoperative renal function (pilot analysis) Трансплантология (Москва) liver transplantation inferior vena cava obstruction postoperative complications acute renal failure |
| title | Impact of inferior vena cava obstruction during orthotopic liver transplantation without venovenous bypass grafting on early postoperative renal function (pilot analysis) |
| title_full | Impact of inferior vena cava obstruction during orthotopic liver transplantation without venovenous bypass grafting on early postoperative renal function (pilot analysis) |
| title_fullStr | Impact of inferior vena cava obstruction during orthotopic liver transplantation without venovenous bypass grafting on early postoperative renal function (pilot analysis) |
| title_full_unstemmed | Impact of inferior vena cava obstruction during orthotopic liver transplantation without venovenous bypass grafting on early postoperative renal function (pilot analysis) |
| title_short | Impact of inferior vena cava obstruction during orthotopic liver transplantation without venovenous bypass grafting on early postoperative renal function (pilot analysis) |
| title_sort | impact of inferior vena cava obstruction during orthotopic liver transplantation without venovenous bypass grafting on early postoperative renal function pilot analysis |
| topic | liver transplantation inferior vena cava obstruction postoperative complications acute renal failure |
| url | https://www.jtransplantologiya.ru/jour/article/view/239 |
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