Polymer carrier selection for creation of diosmin solid dispersion system by hot melt extrusion
Introduction. The extremely unfavorable physical, chemical and functional properties of diosmin, a component of a number of popular phleboprotective drugs, cause an increased therapeutic dosage of the active pharmaceutical ingredient (API) in the dosage form and complicate the manufacturing process....
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Main Authors: | A. A. Danilova, E. V. Vishnyakov, E. S. Surbeeva, K. A. Gusev, D. N. Maimistov, E. V. Flisyuk |
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Format: | Article |
Language: | Russian |
Published: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2023-09-01
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Series: | Разработка и регистрация лекарственных средств |
Subjects: | |
Online Access: | https://www.pharmjournal.ru/jour/article/view/2143 |
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