Hypoxia and Hypoxia‐Reoxygenation Potentiate Helicobacter pylori Infection and Gastric Epithelial Cell Proliferation

Hypoxia and Hypoxia‐Reoxygenation Potentiate Helicobacter pylori Infection and Gastric Epithelial Cell Proliferation

ABSTRACT Introduction The gastric epithelium experiences intermittent hypoxia due to various physiological and pathological conditions. However, the impact of hypoxia and hypoxia‐reoxygenation of gastric epithelial cells (GECs) on Helicobacter pylori‐mediated gastric cancer (GC) has never been inves...

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Main Authors: Indrajit Poirah, Soumyadeep Chakraborty, Pratyush Kumar Padhan, Ashish Kumar Mishra, Debashish Chakraborty, Pragyesh Dixit, Supriya Samal, Niranjan Rout, Shivaram Prasad Singh, Gautam Nath, Duane T. Smoot, Hassan Ashktorab, Asima Bhattacharyya
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Cancer Medicine
Subjects:
carcinoembryonic antigen
Helicobacter pylori, hypoxia
hypoxia‐inducible factor 1
hypoxia‐reoxygenation
NADPH oxidase 4
reactive oxygen species
Online Access:https://doi.org/10.1002/cam4.70860
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