Dying occurs as a defined molecular progression in Drosophila rather than as nonspecific physiological collapse

Summary: While we know much about aging, dying remains mysterious. Here, we show that old-age death in Drosophila is an orderly process that follows, but is distinguishable from, aging itself. We apply pseudotime trajectory analysis to transcriptomic data from individual flies as they approach death...

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Bibliographic Details
Main Authors: Andrew W. Scott, Andrew P.K. Wodrich, Hitesh S. Chaouhan, Arvind K. Shukla, Kory Johnson, Philip G. McQueen, Edward Giniger
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225013768
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