MECHANISMS OF FORMATION OF KIDNEY FIBROSIS BASED ON MICROVASCULAR LESIONS

The review deals with the description of the mechanisms involved in the formation of kidney fibrosis. Presented molecular factors activation of the pathological process, signaling pathways, competent cells with synthetic provospolitelnyh mediators, the role of epithelial-mesenchymal transition in th...

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Bibliographic Details
Main Author: E. S. Levitskaya
Format: Article
Language:English
Published: State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation 2017-03-01
Series:Медицинский вестник Юга России
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Online Access:https://www.medicalherald.ru/jour/article/view/487
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Summary:The review deals with the description of the mechanisms involved in the formation of kidney fibrosis. Presented molecular factors activation of the pathological process, signaling pathways, competent cells with synthetic provospolitelnyh mediators, the role of epithelial-mesenchymal transition in the development and progression of renal fibrosis. Demonstrated evidence of the importance of the remodeling of the renal arteries of small diameter in the development and progression of renal fibrosis tissue. Sources of information on topics Review article full disclosure, a presentation of the current views on the study of this problem, use the database PubMed citations, RISC, Scopus, Web- Mathematical Sciences, Google Scholar, Copernicus index, Ulrich Periodicals Directory.
ISSN:2219-8075
2618-7876