Autonomous dysfunction in patients with metabolic syndrome: heart rate variability study
Aim. To assess autonomous regulation of heart rhythm in metabolic syndrome (MS) patients and clinically healthy individuals, using heart rate variability (HRV) analysis. Material and methods. The main group included 23 MS patients, the control group – 22 healthy individuals. All participants underwe...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2005-08-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/992 |
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| author | D. A. Anichkov N. A. Shostak L. A. Kotlyarova D. S. Ivanov |
| author_facet | D. A. Anichkov N. A. Shostak L. A. Kotlyarova D. S. Ivanov |
| author_sort | D. A. Anichkov |
| collection | DOAJ |
| description | Aim. To assess autonomous regulation of heart rhythm in metabolic syndrome (MS) patients and clinically healthy individuals, using heart rate variability (HRV) analysis. Material and methods. The main group included 23 MS patients, the control group – 22 healthy individuals. All participants underwent 24-hour Holter ECG monitoring, with temporal HRV analysis. Results. In MS patients, all HRV parameters were significantly lower than in healthy individuals (p<0.001). Nevertheless, after including mean 24-hour HR into analysis, the difference between examined HRV parameters became only borderline significant. Similar data was obtained for mean daytime HRV parameters; no difference for mean nighttime HRV parameters was detected after adjustment for HR and age. Conclusion. MS patients demonstrated autonomous dysfunction, manifested as relative sympathic hypertonus. Autonomous regulation correction can be performed with imidazoline receptor agonists. |
| format | Article |
| id | doaj-art-61dba56b090d4e08bac2ae22dd3f391f |
| institution | Matheson Library |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2005-08-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-61dba56b090d4e08bac2ae22dd3f391f2025-08-04T12:50:09Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252005-08-01448590706Autonomous dysfunction in patients with metabolic syndrome: heart rate variability studyD. A. Anichkov0N. A. Shostak1L. A. Kotlyarova2D. S. Ivanov3Russian State Medical University, MoscowRussian State Medical University, MoscowRussian State Medical University, MoscowRussian State Medical University, MoscowAim. To assess autonomous regulation of heart rhythm in metabolic syndrome (MS) patients and clinically healthy individuals, using heart rate variability (HRV) analysis. Material and methods. The main group included 23 MS patients, the control group – 22 healthy individuals. All participants underwent 24-hour Holter ECG monitoring, with temporal HRV analysis. Results. In MS patients, all HRV parameters were significantly lower than in healthy individuals (p<0.001). Nevertheless, after including mean 24-hour HR into analysis, the difference between examined HRV parameters became only borderline significant. Similar data was obtained for mean daytime HRV parameters; no difference for mean nighttime HRV parameters was detected after adjustment for HR and age. Conclusion. MS patients demonstrated autonomous dysfunction, manifested as relative sympathic hypertonus. Autonomous regulation correction can be performed with imidazoline receptor agonists.https://cardiovascular.elpub.ru/jour/article/view/992metabolic syndromeautonomous nervous systemheart rate variabilityimidazoline receptor agonists |
| spellingShingle | D. A. Anichkov N. A. Shostak L. A. Kotlyarova D. S. Ivanov Autonomous dysfunction in patients with metabolic syndrome: heart rate variability study Кардиоваскулярная терапия и профилактика metabolic syndrome autonomous nervous system heart rate variability imidazoline receptor agonists |
| title | Autonomous dysfunction in patients with metabolic syndrome: heart rate variability study |
| title_full | Autonomous dysfunction in patients with metabolic syndrome: heart rate variability study |
| title_fullStr | Autonomous dysfunction in patients with metabolic syndrome: heart rate variability study |
| title_full_unstemmed | Autonomous dysfunction in patients with metabolic syndrome: heart rate variability study |
| title_short | Autonomous dysfunction in patients with metabolic syndrome: heart rate variability study |
| title_sort | autonomous dysfunction in patients with metabolic syndrome heart rate variability study |
| topic | metabolic syndrome autonomous nervous system heart rate variability imidazoline receptor agonists |
| url | https://cardiovascular.elpub.ru/jour/article/view/992 |
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