Mechanism study on the attenuation of cerebral ischemia–reperfusion injury by LBP extract through regulation of SIRT1/PGC-1α axis

Mechanism study on the attenuation of cerebral ischemia–reperfusion injury by LBP extract through regulation of SIRT1/PGC-1α axis

This study aims to determine if Lycium barbarum polysaccharides (LBP) extract attenuate oxidative stress by regulating the SIRT1/PGC-1α axis, potentially ameliorating oxygen–glucose deprivation/reperfusion (OGD/R)-induced neuronal damage.

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Bibliographic Details
Main Authors: Niu Qingfeng, Peng Jiahui, Zhou Yujia, Li Xiaowen, Liu Ouya, Xin Cheng, Liu Ping, Hei Changchun, Yang Xiao
Format: Article
Language:English
Published: De Gruyter 2025-07-01
Series:Translational Neuroscience
Subjects:
hypoxia-reperfusion
lbp
oxidative stress
sirt1
pgc-1α
ros
Online Access:https://doi.org/10.1515/tnsci-2025-0377
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