Freestyle Bioprosthetic Valves: Clinical Outcomes, Surgical Techniques, and Future Directions
Introduction: The Freestyle® stentless porcine aortic root (Medtronic, Minneapolis, MN) has emerged as a valuable option for aortic valve replacement (AVR), offering superior hemodynamics compared to stented bioprostheses and eliminating the need for lifelong anticoagulation required with mechanica...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Albanian Society for Trauma and Emergency Surgery
2025-07-01
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| Series: | Albanian Journal of Trauma and Emergency Surgery |
| Subjects: | |
| Online Access: | https://journal.astes.org.al/AJTES/index.php/AJTES/article/view/475 |
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| Summary: | Introduction: The Freestyle® stentless porcine aortic root (Medtronic, Minneapolis, MN) has emerged as a valuable option for aortic valve replacement (AVR), offering superior hemodynamics compared to stented bioprostheses and eliminating the need for lifelong anticoagulation required with mechanical valves. Derived from a porcine aortic root, the Freestyle valve allows for versatile implantation techniques, including subcoronary, root inclusion, and full root replacement. While the Freestyle valve demonstrates excellent hemodynamics and benefits, as well as acceptable long-term survival, challenges remain regarding structural valve deterioration (SVD) in younger patients and technical complexities during implantation. These technical complexities include the need for precise surgical expertise, the stentless nature of the prosthesis, dense adhesions, and circumferential calcification of the porcine root. Emerging technologies, such as advanced anti-calcification treatments and tissue engineering, may further enhance its durability. In this article, we present two illustrative cases from our institution to highlight these challenges and discuss surgical strategies, as well as synthesize current evidence and discuss future directions for stentless bioprosthetic valves.
Conclusion: The Medtronic Freestyle stentless bioprosthetic valve offers significant hemodynamic benefits and acceptable durability in appropriately selected patients. However, late failure of the Freestyle stentless aortic root bioprosthetic can present as catastrophic pseudoaneurysm formation or severe leaflet degeneration with rupture. Prosthesis excision requires complex surgical strategies, including the need for root replacement and tailored coronary reimplantation.
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| ISSN: | 2521-8778 2616-4922 |