Effects of Tumour Necrosis Factor Antagonists on Insulin Sensitivity/Resistance in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis.

QR Code

Effects of Tumour Necrosis Factor Antagonists on Insulin Sensitivity/Resistance in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis.

<h4>Objective</h4>Beyond the joints, TNFi (tumour necrosis factor inhibitor) therapy may confer systemic benefits in rheumatoid arthritis (RA). Several studies have investigated the role of TNFi on insulin resistance/sensitivity (IR/IS). This question is of general interest given the eme...

Full description

Saved in:

Bibliographic Details
Main Authors:	Agata N Burska, Rajalingham Sakthiswary, Naveed Sattar
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0128889&type=printable
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Infectious Complications of Anti-Tumour Necrosis Factor-α Therapy in Rheumatoid Arthritis
by: Xynos, Ioannis D., et al.
Published: (2012)

Comparison of IgG4 with inflammatory cytokines (IL-1, IL-6 and TNFα) in rheumatoid arthritis
by: Rajalingham Sakthiswary, et al.
Published: (2025-07-01)

Insulin resistance in rheumatoid arthritis: relationship to lipid metabolism disorders and metabolic syndrome
by: L. V. Kondratyeva, et al.
Published: (2019-07-01)

Deciphering differential biomarkers for anti-interleukin-6 receptor and anti-tumour necrosis factor-α treatment response in rheumatoid arthritis by multiomics analysis
by: Emilie Gerard, et al.
Published: (2025-08-01)

The tumor necrosis factor-α inhibitor golimumab in the treatment of rheumatoid arthritis
by: Natalia Vladimirovna Chichasova
Published: (2014-12-01)

Ihmor necrosis factor-a inhibitors and cardiovascular risk in rheumatoid arthritis
by: Tatiana Valentinovna Popkova, et al.
Published: (2012-12-01)

The clinical significance of vitamin D in systemic lupus erythematosus: a systematic review.
by: Rajalingham Sakthiswary, et al.
Published: (2013-01-01)

USE OF TUMOR NECROSIS FACTOR-A INHIBITORS IN RHEUMATOID ARTHRITIS: TOPICAL ASPECTS
by: E L Luchikhina, et al.
Published: (2008-12-01)

TUMOR NECROSIS FACTOR-α MEMBRANE-BOUND AND SOLUBLE RECEPTORS IN NORM AND IN RHEUMATOID ARTHRITIS
by: A. A. Alshevskaya, et al.
Published: (2012-05-01)

Fiber and Insulin Sensitivity
by: Maki, Kevin C., et al.
Published: (2011)

Anti-Tumour Necrosis Factor-α Induced Systemic Lupus Erythematosus
by: Almoallim, Hani, et al.
Published: (2012)

Tumor necrosis factor-α inhibitors and their effects on cardiovascular risk factorsin patients with rheumatoid arthritis
by: O G Lineva, et al.
Published: (2010-02-01)

DISTURBANCE OF VIBRATION SENSITIVITY DURING RHEUMATOID ARTHRITIS. CLINICAL ASPECTS
by: B. F. Nemtzov, et al.
Published: (2000-02-01)

CARDIOPROTECTIVE EFFECT OF TUMOR NECROSIS FACTOR ALPHA ANTAGONIST IN DOXORUBICIN MYOCARD TOXICITY
by: M. I. Popovich, et al.
Published: (2018-02-01)

Experience with tofacitinib in the treatment of resistant rheumatoid arthritis
by: A. R. Babaeva, et al.
Published: (2015-06-01)

RHEUMATOID ARTHRITIS: THE PROBLEMS OF REMISSION AND THERAPY RESISTANCE
by: E. L. Nasonov, et al.
Published: (2018-07-01)

Revolutionizing Allogeneic Graft Tolerance Through Chimeric Antigen Receptor-T Regulatory Cells
by: Alvin Man Lung Chan, et al.
Published: (2025-07-01)

Disseminated tuberculosis in a patient on anti-tumour necrosis factor (anti-TNF) therapy
by: Shantella Black, et al.
Published: (2025-07-01)

Molecular mechanisms of the development of the phenomena of peripheral and central sensitization in rheumatoid arthritis
by: A. S. Potapova
Published: (2023-03-01)

Insulin-Like-Growth Factor-Binding-Protein 7: An Antagonist to Breast Cancer
by: Benatar, Tania, et al.
Published: (2011)

Multidrug resistance factor - glycoprotein P in rheumatoid arthritis
by: I P Kolosova
Published: (2003-02-01)

Insulin Predicts Methotrexate Response by Affecting the Transcription of Methotrexate Target Genes in the Treatment-Naive Rheumatoid Arthritis
by: Victoria M. E. Lundgren, et al.
Published: (2025-06-01)

Olokizumab, a monoclonal antibody against interleukin-6, in combination with methotrexate in patients with rheumatoid arthritis inadequately controlled by tumour necrosis factor inhibitor therapy: efficacy and safety results of a randomised controlled phase III study
by: E. Feist, et al.
Published: (2023-04-01)

Central sensitization reduces the satisfaction of patients with rheumatoid arthritis. The data of prospective study
by: A. S. Potapova, et al.
Published: (2024-11-01)

IFNα-INDUCED DENDRITIC CELLS IN PATIENTS WITH RHEUMATOID ARTHRITIS AND THEIR SENSITIVITY TO DEXAMETHASONE
by: E. R. Chernykh, et al.
Published: (2017-07-01)

Insulin Resistance and Cardiomyopathy
by: Huang, Jiung-Pang, et al.
Published: (2012)

Tofacitinib is a modern solution to the problem of resistant rheumatoid arthritis
by: I. V. Menshikova, et al.
Published: (2019-05-01)

Tumor necrosis factor-? inhibitors in therapy for psoriatic arthritis
by: Vladimir Vasilyevich Badokin, et al.
Published: (2010-12-01)

Indicative features of tissue and microbial sensitization in the pathogenesis of generalized parodontitis associated with rheumatoid arthritis
by: A.M. Proschenko, et al.
Published: (2024-06-01)

INTERGENIC INTERACTIONS OF TUMOR NECROSIS FACTOR ALPHA, INTERLEUKIN 17, AND OSTEOPROTEGERIN IN THE IMMUNOPATHOGENESIS OF RHEUMATOID ARTHRITIS IN THE RUSSIAN POPULATION OF THE CHELYABINSK REGION
by: Yulia Chumacheva, et al.
Published: (2019-08-01)

Resistance Training for Patients with Rheumatoid Arthritis: Effects on Disability, Rheumatoid Cachexia, and Osteoporosis; and Recommendations for Prescription
by: Lemmey, Andrew B.
Published: (2012)

Effect of interleukin 6 blockers on body composition, adipocytokines and insulin-like growth factor 1 in patients with rheumatoid arthritis
by: L. V. Kondratyeva, et al.
Published: (2025-07-01)

Effect of tofacitinib on patient-reported outcomes in patients with active psoriatic arthritis and an inadequate response to tumour necrosis factor inhibitors in the phase III, randomised controlled trial: OPAL Beyond
by: Philip J Mease, et al.
Published: (2019-06-01)

Discontinuation and switching patterns of tumour necrosis factor inhibitors (TNFis) in TNFi-naive and TNFi-experienced patients with psoriatic arthritis: an observational study from the US-based Corrona registry
by: Philip J Mease, et al.
Published: (2019-06-01)

An insulin-sensitive Drosophila insulin-like receptor mutant remodels methionine metabolism to extend lifespan.
by: Marc Tatar, et al.
Published: (2025-06-01)

Unravelling the pathways driving tumour growth and resistance
by: Abraham Ubhenin, et al.
Published: (2025-06-01)

Insulin Resistance and Alzheimer’s Disease
by: Son, Sung Min, et al.
Published: (2011)

Nimesulide in rheumatoid arthritis
by: E. L. Luchikhina
Published: (2015-06-01)

Osteoporosis in Rheumatoid Arthritis
by: Geraci, Alessandro
Published: (2012)

RHEUMATOID ARTHRITIS AND PREGNANCY
by: N. M. Kosheleva, et al.
Published: (2014-12-01)