Mitochondrial fission regulator 2 promotes cell proliferation, migration and invasion in hepatocellular carcinoma through regulating PI3K/AKT signaling pathway
Abstract Objective Mitochondrial fission regulator 2 (MTFR2) is upregulated in multiple cancers, including hepatocellular carcinoma (HCC); however, its mechanistic role in HCC progression remains poorly understood. Methods MTFR2 expression in HCC tissues was analyzed using TCGA and GEO databases. Va...
Saved in:
Main Authors: | Qiang Sun, Kaikun Liu, Fangjie Zheng, Xinwei Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2025-06-01
|
Series: | Cell Division |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13008-025-00160-2 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Diethylhexyl phthalate exposure promotes mitophagy through Drp1-mediated mitochondrial fission in neural crest cells of chick embryos
by: Yi Li, et al.
Published: (2025-09-01) -
Mechanistic study of modulating mitochondrial fission and fusion to ameliorate neuropathic pain in mice
by: Liu Xie, et al.
Published: (2025-05-01) -
FAM105B Promotes Hepatocellular Carcinoma Progression and Metastasis by Activating the PI3K/AKT/MTOR Signaling Pathway and Inducing Epithelial-Mesenchymal Transition
by: Yang LL, et al.
Published: (2025-07-01) -
m6A‐Mediated TMCO3 Promotes Hepatocellular Carcinoma Progression by Facilitating the Membrane Translocation and Activation of AKT
by: Xinxin Li, et al.
Published: (2025-07-01) -
STOX1 Isoform A Promotes Proliferation and Progression of Hepatocellular Carcinoma by Dual Mechanisms of Transcriptionally Upregulation of Cyclin B1 and Activation of ROS‐Dependent PTEN/AKT1 Signaling
by: Chunlin Jiang, et al.
Published: (2025-07-01)