Dot1l Regulates the Spontaneous Bone Regeneration of Periosteum-Derived Stem Cells by Regulating Chac1 Expression

Conclusions: Our study suggests that mandibular defects can induce the activation of PDSCs and inhibit the expression of Dot1l, potentially affecting the Notch signaling pathway. Targeting the Dot1l/Chac1 pathway to regulate the osteogenic differentiation of PDSCs lays a solid foundation for periost...

Full description

Saved in:
Bibliographic Details
Main Authors: Taoran Jiang, Bin Fang, Zheyuan Yu, Dejun Cao
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/sci/1508850
Tags: Add Tag
No Tags, Be the first to tag this record!