Sorafenib induces ferroptosis in human renal cell carcinoma cells through CCAT/enhancer-binding protein homologous protein
Sorafenib, a multi-kinase inhibitor, has been shown to induce ferroptosis, a form of lipid peroxidation-mediated cell death. However, a mechanism of how sorafenib-induced ER stress leads to ferroptosis remains unclear. Here, we report that the CCAT/enhancer-binding protein (C/EBP) homologous protein...
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Main Authors: | Dinh Thi Nhung, Obadah E.A. Yousif, Byungsuk Kwon |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-09-01
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Series: | Biochemistry and Biophysics Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405580825002304 |
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