Prevalence of Urinary Tract Infections in Term and Preterm Neonates with Prolonged Jaundice
Background: Our objective is to find out the prevalence of urinary tract infections (UTI) among neonates with prolonged jaundice, and to review their clinical characteristics, causative microorganisms, treatment used, and underlying renal structural abnormalities.Methods: This is a retrospective cro...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2025-07-01
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| Series: | Iranian Journal of Neonatology |
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| Online Access: | https://ijn.mums.ac.ir/article_26178_c32e69869278372883752e6da0f2636c.pdf |
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| author | Jumana Albaramki Waheed Hammad Tamer Barakat Mohammad Al-Sanouri Awwab Hammad Fareed Ahmad |
| author_facet | Jumana Albaramki Waheed Hammad Tamer Barakat Mohammad Al-Sanouri Awwab Hammad Fareed Ahmad |
| author_sort | Jumana Albaramki |
| collection | DOAJ |
| description | Background: Our objective is to find out the prevalence of urinary tract infections (UTI) among neonates with prolonged jaundice, and to review their clinical characteristics, causative microorganisms, treatment used, and underlying renal structural abnormalities.Methods: This is a retrospective cross-sectional study of neonates with prolonged jaundice over a 5-year period at Jordan University Hospital. The study included term and preterm neonates less than 5 weeks of age with prolonged hyperbilirubinemia which was defined as persistent elevation of serum bilirubin of more than 8 mg/dl in term neonates more than two weeks of age and more than three weeks for the preterm neonates.Results: 280 newborns had prolonged jaundice and the majority were full term. The two most common causes for prolonged jaundice were urinary tract infection and breast milk jaundice. The prevalence of urinary tract infection in our study was high, reaching 33.9 %. Escherichia coli was the most common organism in neonates with UTI. Renal anomalies were detected in 9.5%. In term neonates, the mean age of presentation and the highest bilirubin levels recorded were significantly higher in neoantes with prolonged jaundice caused by UTI compared to other cause of prolonged jaundice (p<0.05).Conclusion: Our study showed a high rate of UTI in neonates with prolonged jaundice especially in preterm neonates which necessitates appropriate screening and management of UTI in prolonged jaundiced neonates. |
| format | Article |
| id | doaj-art-57e5eb8b88e84d6ea2d2486fdeaf4dd6 |
| institution | Matheson Library |
| issn | 2251-7510 2322-2158 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Neonatology |
| spelling | doaj-art-57e5eb8b88e84d6ea2d2486fdeaf4dd62025-07-30T05:11:01ZengMashhad University of Medical SciencesIranian Journal of Neonatology2251-75102322-21582025-07-01163243010.22038/ijn.2025.76877.249626178Prevalence of Urinary Tract Infections in Term and Preterm Neonates with Prolonged JaundiceJumana Albaramki0Waheed Hammad1Tamer Barakat2Mohammad Al-Sanouri3Awwab Hammad4Fareed Ahmad5Department of Pediatrics ,School of Medicine, The University of Jordan, Amman, JordanSchool of Medicine, The University of Jordan, Amman, JordanSchool of Medicine, The University of Jordan, Amman, JordanDepartment of Anesthesia and Intensive Care, School of Medicine, The University of Jordan, Amman, JordanSchool of Medicine, The University of Jordan, Amman, JordanDepartment of Pediatrics ,School of Medicine, The University of Jordan, Amman, JordanBackground: Our objective is to find out the prevalence of urinary tract infections (UTI) among neonates with prolonged jaundice, and to review their clinical characteristics, causative microorganisms, treatment used, and underlying renal structural abnormalities.Methods: This is a retrospective cross-sectional study of neonates with prolonged jaundice over a 5-year period at Jordan University Hospital. The study included term and preterm neonates less than 5 weeks of age with prolonged hyperbilirubinemia which was defined as persistent elevation of serum bilirubin of more than 8 mg/dl in term neonates more than two weeks of age and more than three weeks for the preterm neonates.Results: 280 newborns had prolonged jaundice and the majority were full term. The two most common causes for prolonged jaundice were urinary tract infection and breast milk jaundice. The prevalence of urinary tract infection in our study was high, reaching 33.9 %. Escherichia coli was the most common organism in neonates with UTI. Renal anomalies were detected in 9.5%. In term neonates, the mean age of presentation and the highest bilirubin levels recorded were significantly higher in neoantes with prolonged jaundice caused by UTI compared to other cause of prolonged jaundice (p<0.05).Conclusion: Our study showed a high rate of UTI in neonates with prolonged jaundice especially in preterm neonates which necessitates appropriate screening and management of UTI in prolonged jaundiced neonates.https://ijn.mums.ac.ir/article_26178_c32e69869278372883752e6da0f2636c.pdfhyperbilirubinemiaprolonged jaundiceurinary tract infection |
| spellingShingle | Jumana Albaramki Waheed Hammad Tamer Barakat Mohammad Al-Sanouri Awwab Hammad Fareed Ahmad Prevalence of Urinary Tract Infections in Term and Preterm Neonates with Prolonged Jaundice Iranian Journal of Neonatology hyperbilirubinemia prolonged jaundice urinary tract infection |
| title | Prevalence of Urinary Tract Infections in Term and Preterm Neonates with Prolonged Jaundice |
| title_full | Prevalence of Urinary Tract Infections in Term and Preterm Neonates with Prolonged Jaundice |
| title_fullStr | Prevalence of Urinary Tract Infections in Term and Preterm Neonates with Prolonged Jaundice |
| title_full_unstemmed | Prevalence of Urinary Tract Infections in Term and Preterm Neonates with Prolonged Jaundice |
| title_short | Prevalence of Urinary Tract Infections in Term and Preterm Neonates with Prolonged Jaundice |
| title_sort | prevalence of urinary tract infections in term and preterm neonates with prolonged jaundice |
| topic | hyperbilirubinemia prolonged jaundice urinary tract infection |
| url | https://ijn.mums.ac.ir/article_26178_c32e69869278372883752e6da0f2636c.pdf |
| work_keys_str_mv | AT jumanaalbaramki prevalenceofurinarytractinfectionsintermandpretermneonateswithprolongedjaundice AT waheedhammad prevalenceofurinarytractinfectionsintermandpretermneonateswithprolongedjaundice AT tamerbarakat prevalenceofurinarytractinfectionsintermandpretermneonateswithprolongedjaundice AT mohammadalsanouri prevalenceofurinarytractinfectionsintermandpretermneonateswithprolongedjaundice AT awwabhammad prevalenceofurinarytractinfectionsintermandpretermneonateswithprolongedjaundice AT fareedahmad prevalenceofurinarytractinfectionsintermandpretermneonateswithprolongedjaundice |