Melatonin protects chicken follicular granulosa cells against oxidative damage-induced apoptosis via inhibiting FOXO1 signaling pathway

Melatonin protects chicken follicular granulosa cells against oxidative damage-induced apoptosis via inhibiting FOXO1 signaling pathway

In laying hens, the age-related decline in egg production efficiency is largely attributed to ovarian dysfunction and increased follicular atresia, which are aggravated by oxidative damage mediated by reactive oxygen species (ROS). Melatonin (Mel) demonstrates powerful antioxidant capabilities, whic...

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Bibliographic Details
Main Authors: Xuelu Liu, Keqian Di, Xiangyu Chen, Chenxuan Huang, Fei Hou, Jianku Hou, Erying Hao, Kang Bai, Dehe Wang, Lei Shi, Yifan Chen, Hui Chen
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Poultry Science
Subjects:
Melatonin, Oxidative stress, Follicular
Granulosa cell, FOXO1
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579125007163
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