Synoviolin alleviates GSDMD‐mediated periodontitis by suppressing its stability
Abstract Introduction Inflammasome and pyroptosis play important roles in periodontitis. Gasdermin D (GSDMD), a key factor in pyroptosis, is cleaved by caspase‐1 and regulated by ubiquitination. Synoviolin is a ubiquitin E3 ligase that interacts with GSDMD. In this study, the effects of Synoviolin o...
Saved in:
Main Authors: | Ying Pang, Lili Liu, Shuainan Wu, Jianqi Wang, Lu Liu |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2023-07-01
|
Series: | Immunity, Inflammation and Disease |
Subjects: | |
Online Access: | https://doi.org/10.1002/iid3.880 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
STING regulates NETs formation by activating GSDMD in influenza viral pneumonia
by: Rongrong Huang, et al.
Published: (2025-07-01) -
HIC1 suppresses Tumor Progression and Enhances CD8+ T Cells Infiltration Through Promoting GSDMD‐induced Pyroptosis in Gastric Cancer
by: Mengjie Kang, et al.
Published: (2025-07-01) -
Ellagic acid alleviates NLRP6/caspase-1/GSDMD-mediated inflammation and pyroptosis in rats post cerebral ischemia/reperfusion injury
by: Ling Hu, et al.
Published: (2025-01-01) -
AIM2-Driven Inflammation in Periodontitis: Mechanisms and Systemic Implications
by: Fan Z, et al.
Published: (2025-05-01) -
The Reevaluation of Subgingival Calculus: A Narrative Review
by: Stephen K. Harrel, et al.
Published: (2025-06-01)