No associations between HIV reservoir and inflammation in long-term virally suppressed dolutegravir-based ART-treated individuals

No associations between HIV reservoir and inflammation in long-term virally suppressed dolutegravir-based ART-treated individuals

IntroductionDespite effective antiretroviral therapy (ART), people with HIV (PWH) experience persistent immune activation and inflammation, increasing the risk of non-AIDS-related comorbidities. The contribution of the HIV reservoir to this chronic inflammatory state remains debated. Understanding t...

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Bibliographic Details
Main Authors: Céline Fombellida-Lopez, Diego Aguilar Ortmans, Michel Moutschen, Alexander O. Pasternak, Gilles Darcis
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
HIV reservoir
inflammation
immune activation
correlation
antiretroviral therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1628086/full
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