Progress in perioperative use of dexmedetomidine in elderly lung cancer patients
Elderly patients demonstrate diminished physiological functions and various comorbidities, which present significant challenges in the perioperative anesthesia management of lung cancer surgery. Dexmedetomidine, a selective α2-adrenergic receptor agonist, demonstrates dose-dependent effects includin...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Chinese |
| Published: |
Editorial Office of International Journal of Geriatrics
2025-07-01
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| Series: | Guoji laonian yixue zazhi |
| Subjects: | |
| Online Access: | http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.04.019&lang=en |
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| Summary: | Elderly patients demonstrate diminished physiological functions and various comorbidities, which present significant challenges in the perioperative anesthesia management of lung cancer surgery. Dexmedetomidine, a selective α2-adrenergic receptor agonist, demonstrates dose-dependent effects including sedation, analgesia, anxiolysis, and antisympathetic activity. The dexmedetomidine demonstrates the protective potential across multiple organs during the perioperative period of lung cancer surgery in the elderly, highlighting its significant application value in clinical anesthesia practice. This article reviews the mechanisms of dexmedetomidine and its potential for multi-organ protection during the perioperative period of lung cancer surgery in elderly patients. It also discusses recent advances in clinical anesthesia practice, aiming to enhance the quality and safety of dexmedetomidine-based anesthesia management for this demographic. |
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| ISSN: | 1674-7593 |