Asarum sieboldii, a Potential Ethnomedicinal Herb in Dentistry and Oral Health
ABSTRACT: Asarum sieboldii, a species of wild ginger native to East Asia, has long been recognised as an important herb in Asian traditional medicine. It has been applied in the treatment of toothache, cough, asthma, and sinusitis. A. sieboldii has gained global interest because it offers solutions...
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Elsevier
2025-08-01
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| Series: | International Dental Journal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0020653925001054 |
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| author | Kenneth Happy Joyce Mudondo Nam-Hui Yim Youngmin Kang |
| author_facet | Kenneth Happy Joyce Mudondo Nam-Hui Yim Youngmin Kang |
| author_sort | Kenneth Happy |
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| description | ABSTRACT: Asarum sieboldii, a species of wild ginger native to East Asia, has long been recognised as an important herb in Asian traditional medicine. It has been applied in the treatment of toothache, cough, asthma, and sinusitis. A. sieboldii has gained global interest because it offers solutions to multiple health concerns. The plant is renowned for its anti-inflammatory, analgesic, antimicrobial, antifungal, and antioxidant properties. Its roots exhibit a wide range of biological and pharmacological effects. The plant contains several chemical constituents, including methyleugenol, 3,4,5-trimethoxytoluene, and safrole, which contribute to its medicinal benefits. Whereas literature search highlights the potential application of A. sieboldii in herbal medicine, to date its application in dentistry remains largely unexplored, with the existing literature vastly fragmented in various sources. This review therefore, provides a comprehensive overview of the potential application of A. sieboldii in dentistry and oral health. The plant shows considerable promise and appears to be effective for managing common oral diseases such as tooth decay, periodontal diseases, toothache, oral cancer, oral ulcers, and gingivitis. Its ability to inhibit nitric oxide release, along with its neuroprotective effects, further enhances its potential for relieving pain and inflammation. With these therapeutic benefits, A. sieboldii presents a promising natural alternative or a complementary option to conventional dental treatments, capable of addressing a wide range of oral health conditions. The findings from this review could serve as a solid foundation for future research, supporting the development of high-quality, safe, and effective A. sieboldii–based products in dentistry and oral health. |
| format | Article |
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| institution | Matheson Library |
| issn | 0020-6539 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Elsevier |
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| series | International Dental Journal |
| spelling | doaj-art-554ca6b35c2f43d08c5f2c9deac01b7c2025-07-15T04:15:45ZengElsevierInternational Dental Journal0020-65392025-08-01754100816Asarum sieboldii, a Potential Ethnomedicinal Herb in Dentistry and Oral HealthKenneth Happy0Joyce Mudondo1Nam-Hui Yim2Youngmin Kang3Korean Convergence Medical Science Major, University of Science and Technology, Daejeon, Republic of Korea; Herbal Medicine Resources Research Center, Korea Institute of Oriental Medicine, Naju-Si, Jeollanam-Do, Republic of KoreaKorean Convergence Medical Science Major, University of Science and Technology, Daejeon, Republic of Korea; Herbal Medicine Resources Research Center, Korea Institute of Oriental Medicine, Naju-Si, Jeollanam-Do, Republic of KoreaKorean Medicine Application Center, Korea Institute of Oriental Medicine, Dong-gu, Daegu, Republic of KoreaKorean Convergence Medical Science Major, University of Science and Technology, Daejeon, Republic of Korea; Herbal Medicine Resources Research Center, Korea Institute of Oriental Medicine, Naju-Si, Jeollanam-Do, Republic of Korea; Corresponding author. Department of Oriental Medicine Convergence Science, Korean Institute of Oriental Medicine, Oriental Medicine Resources Research Center, 111 Geonjae-ro, Naju-si, Jeollanam-do, Daho-dong 58245, Republic of Korea.ABSTRACT: Asarum sieboldii, a species of wild ginger native to East Asia, has long been recognised as an important herb in Asian traditional medicine. It has been applied in the treatment of toothache, cough, asthma, and sinusitis. A. sieboldii has gained global interest because it offers solutions to multiple health concerns. The plant is renowned for its anti-inflammatory, analgesic, antimicrobial, antifungal, and antioxidant properties. Its roots exhibit a wide range of biological and pharmacological effects. The plant contains several chemical constituents, including methyleugenol, 3,4,5-trimethoxytoluene, and safrole, which contribute to its medicinal benefits. Whereas literature search highlights the potential application of A. sieboldii in herbal medicine, to date its application in dentistry remains largely unexplored, with the existing literature vastly fragmented in various sources. This review therefore, provides a comprehensive overview of the potential application of A. sieboldii in dentistry and oral health. The plant shows considerable promise and appears to be effective for managing common oral diseases such as tooth decay, periodontal diseases, toothache, oral cancer, oral ulcers, and gingivitis. Its ability to inhibit nitric oxide release, along with its neuroprotective effects, further enhances its potential for relieving pain and inflammation. With these therapeutic benefits, A. sieboldii presents a promising natural alternative or a complementary option to conventional dental treatments, capable of addressing a wide range of oral health conditions. The findings from this review could serve as a solid foundation for future research, supporting the development of high-quality, safe, and effective A. sieboldii–based products in dentistry and oral health.http://www.sciencedirect.com/science/article/pii/S0020653925001054Asarum sieboldiiAnti-inflammatoryAntimicrobialNanotechnologyPeriodontal diseasesDetoxification |
| spellingShingle | Kenneth Happy Joyce Mudondo Nam-Hui Yim Youngmin Kang Asarum sieboldii, a Potential Ethnomedicinal Herb in Dentistry and Oral Health International Dental Journal Asarum sieboldii Anti-inflammatory Antimicrobial Nanotechnology Periodontal diseases Detoxification |
| title | Asarum sieboldii, a Potential Ethnomedicinal Herb in Dentistry and Oral Health |
| title_full | Asarum sieboldii, a Potential Ethnomedicinal Herb in Dentistry and Oral Health |
| title_fullStr | Asarum sieboldii, a Potential Ethnomedicinal Herb in Dentistry and Oral Health |
| title_full_unstemmed | Asarum sieboldii, a Potential Ethnomedicinal Herb in Dentistry and Oral Health |
| title_short | Asarum sieboldii, a Potential Ethnomedicinal Herb in Dentistry and Oral Health |
| title_sort | asarum sieboldii a potential ethnomedicinal herb in dentistry and oral health |
| topic | Asarum sieboldii Anti-inflammatory Antimicrobial Nanotechnology Periodontal diseases Detoxification |
| url | http://www.sciencedirect.com/science/article/pii/S0020653925001054 |
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