Fasting-mimicking diet enhances EGFR-TKI efficacy in oral cancer through dual mechanisms: direct cancer cell sensitization and tumor-associated macrophage crosstalk

BackgroundEmerging evidence suggests the fasting-mimicking diet (FMD) offers a promising alternative to traditional calorie restriction and intermittent fasting, mitigating associated adverse effects including cachexia. Clinical trials have demonstrated the safety and efficacy of FMD, highlighting i...

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Main Authors: Lei Wang, Yu-jie Wang, Rong Wang, Fu-lian Gong, Ji-Yuan Chen, Ya-ting Yu, Ze-rong Qiu, Yong-fang Yuan
格式: Article
語言:英语
出版: Frontiers Media S.A. 2025-07-01
叢編:Frontiers in Pharmacology
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fphar.2025.1641024/full
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