Breath-holding index – a new approach to an old method
Background: Despite technical challenges and uncertainties, transcranial Doppler (TCD) ultrasonography remains a promising tool due to its non-invasive nature, safety, and cost-effectiveness. In this study we aimed to develop an advanced automatic calculation method for the breath-holding index (BHI...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Medical University of Gdańsk
2025-07-01
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| Series: | European Journal of Translational and Clinical Medicine |
| Subjects: | |
| Online Access: | https://ejtcm.gumed.edu.pl/articles/204417.pdf |
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| Summary: | Background: Despite technical challenges and uncertainties, transcranial Doppler (TCD) ultrasonography remains a promising tool due to its non-invasive nature, safety, and cost-effectiveness. In this study we aimed to develop an advanced automatic calculation method for the breath-holding index (BHI) to enhance the reliability of cerebrovascular reactivity (CVR) measurements. Material and methods: This study involved the automatic calculation of BHI during the breath-holding maneuver, targeting a reduction in variability and an increase in the accuracy of CVR assessment. Results: The BHI_to_max method was identified as the most effective, which revealed the least variability. This method calculates the steepest slope of blood flow velocity change during CO<sub>2</sub>-induced vasodilation. By focusing on a minimized time interval and adjusting for potential shifts in the start and end points, this approach captures the most dynamic phase of the cerebrovascular response to CO<sub>2</sub> . Conclusions: We propose an automatic calculation method, which accounts for individual differences in CO<sub>2</sub> sensitivity and CVR. It offers a potentially more precise and personalized assessment of CVR, leading to a more reproducible and individualized measurement. |
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| ISSN: | 2657-3148 2657-3156 |