A case of gastric and duodenal mucosa-associated lymphoid tissue lymphoma with multiple gastric cancers: a case report
Abstract Background Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is often caused by Helicobacter pylori and has a good prognosis. Rarely, patients with MALT lymphoma may have gastric cancer and have a poor prognosis. Case presentation We herein report a case in which surgical treatment...
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Japan Surgical Society
2021-01-01
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| Series: | Surgical Case Reports |
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| Online Access: | https://doi.org/10.1186/s40792-020-01081-8 |
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| author | Takashi Yokoyama Tetsuya Tanaka Suzuka Harada Takeshi Ueda Goki Ejiri Shoh Sasaki Maiko Takeda Atsushi Yoshimura |
| author_facet | Takashi Yokoyama Tetsuya Tanaka Suzuka Harada Takeshi Ueda Goki Ejiri Shoh Sasaki Maiko Takeda Atsushi Yoshimura |
| author_sort | Takashi Yokoyama |
| collection | DOAJ |
| description | Abstract Background Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is often caused by Helicobacter pylori and has a good prognosis. Rarely, patients with MALT lymphoma may have gastric cancer and have a poor prognosis. Case presentation We herein report a case in which surgical treatment was achieved for a 72-year-old male patient with gastric and duodenal MALT lymphoma coexisting multiple gastric cancers. He underwent upper endoscopy for epigastric discomfort, which revealed mucosal erosion on the posterior wall of the middle body of the stomach, an elevated lesion on the duodenal bulb, and a raised tumor on the antrum of the stomach. He was diagnosed with gastric and duodenal MALT lymphoma with early gastric cancer. One month after H. pylori eradication, a second upper endoscopy revealed no improvement in the gastric or duodenal mucosa, and areas of strong redness with a shallow recess just below the cardia of the stomach. As a result, a diagnosis of gastric and duodenal MALT lymphoma with two gastric cancers was made. Total gastrectomy with proximal duodenum resection using intraoperative upper endoscopy and regional lymph node dissection was performed. Pathologically, gastric and duodenal MALT lymphoma and three gastric cancers were detected. Since one of them was an advanced cancer, he started taking S-1 after his general condition improved. Conclusion For early detection of gastric and duodenal MALT lymphoma or gastric cancer, appropriate upper endoscopy and a biopsy are important. It is necessary to select a suitable treatment, such as H. pylori eradication, endoscopic treatment, surgery, chemotherapy, and irradiation, according to the disease state. |
| format | Article |
| id | doaj-art-53d74663fbb64dd29c8e2d5ee94d85c1 |
| institution | Matheson Library |
| issn | 2198-7793 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Japan Surgical Society |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj-art-53d74663fbb64dd29c8e2d5ee94d85c12025-08-02T08:05:28ZengJapan Surgical SocietySurgical Case Reports2198-77932021-01-01711610.1186/s40792-020-01081-8A case of gastric and duodenal mucosa-associated lymphoid tissue lymphoma with multiple gastric cancers: a case reportTakashi Yokoyama0Tetsuya Tanaka1Suzuka Harada2Takeshi Ueda3Goki Ejiri4Shoh Sasaki5Maiko Takeda6Atsushi Yoshimura7Department of Surgery, Minami-Nara General Medical CenterDepartment of Surgery, Minami-Nara General Medical CenterDepartment of Surgery, Minami-Nara General Medical CenterDepartment of Surgery, Minami-Nara General Medical CenterDepartment of Surgery, Minami-Nara General Medical CenterDepartment of Pathology, Nara Medical University HospitalDepartment of Pathology, Nara Medical University HospitalDepartment of Surgery, Minami-Nara General Medical CenterAbstract Background Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is often caused by Helicobacter pylori and has a good prognosis. Rarely, patients with MALT lymphoma may have gastric cancer and have a poor prognosis. Case presentation We herein report a case in which surgical treatment was achieved for a 72-year-old male patient with gastric and duodenal MALT lymphoma coexisting multiple gastric cancers. He underwent upper endoscopy for epigastric discomfort, which revealed mucosal erosion on the posterior wall of the middle body of the stomach, an elevated lesion on the duodenal bulb, and a raised tumor on the antrum of the stomach. He was diagnosed with gastric and duodenal MALT lymphoma with early gastric cancer. One month after H. pylori eradication, a second upper endoscopy revealed no improvement in the gastric or duodenal mucosa, and areas of strong redness with a shallow recess just below the cardia of the stomach. As a result, a diagnosis of gastric and duodenal MALT lymphoma with two gastric cancers was made. Total gastrectomy with proximal duodenum resection using intraoperative upper endoscopy and regional lymph node dissection was performed. Pathologically, gastric and duodenal MALT lymphoma and three gastric cancers were detected. Since one of them was an advanced cancer, he started taking S-1 after his general condition improved. Conclusion For early detection of gastric and duodenal MALT lymphoma or gastric cancer, appropriate upper endoscopy and a biopsy are important. It is necessary to select a suitable treatment, such as H. pylori eradication, endoscopic treatment, surgery, chemotherapy, and irradiation, according to the disease state.https://doi.org/10.1186/s40792-020-01081-8Gastric MALT lymphomaDuodenal MALT lymphomaGastric cancerMultiple cancers |
| spellingShingle | Takashi Yokoyama Tetsuya Tanaka Suzuka Harada Takeshi Ueda Goki Ejiri Shoh Sasaki Maiko Takeda Atsushi Yoshimura A case of gastric and duodenal mucosa-associated lymphoid tissue lymphoma with multiple gastric cancers: a case report Surgical Case Reports Gastric MALT lymphoma Duodenal MALT lymphoma Gastric cancer Multiple cancers |
| title | A case of gastric and duodenal mucosa-associated lymphoid tissue lymphoma with multiple gastric cancers: a case report |
| title_full | A case of gastric and duodenal mucosa-associated lymphoid tissue lymphoma with multiple gastric cancers: a case report |
| title_fullStr | A case of gastric and duodenal mucosa-associated lymphoid tissue lymphoma with multiple gastric cancers: a case report |
| title_full_unstemmed | A case of gastric and duodenal mucosa-associated lymphoid tissue lymphoma with multiple gastric cancers: a case report |
| title_short | A case of gastric and duodenal mucosa-associated lymphoid tissue lymphoma with multiple gastric cancers: a case report |
| title_sort | case of gastric and duodenal mucosa associated lymphoid tissue lymphoma with multiple gastric cancers a case report |
| topic | Gastric MALT lymphoma Duodenal MALT lymphoma Gastric cancer Multiple cancers |
| url | https://doi.org/10.1186/s40792-020-01081-8 |
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