Intra-arterial chemoembolization as a component of neoadjuvant treatment of rectal cancer. Literature review

Interventional oncology is a rapidly evolving field of cancer treatment. Minimally invasive techniques, such as transarterial embolization with chemotherapeutic and radioactive agents, are common treatments and are found in many guidelines for the treatment of primary and metastatic liver lesions. I...

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Main Authors: R. E. Kalinin, E. P. Kulikov, N. I. Verkin, S. A. Mertsalov, E. Yu. Golovkin, I. N. Shanaev, O .V. Zotova
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Siberian Branch Publishing House 2024-11-01
Series:Сибирский научный медицинский журнал
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Online Access:https://sibmed.elpub.ru/jour/article/view/1697
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author R. E. Kalinin
E. P. Kulikov
N. I. Verkin
S. A. Mertsalov
E. Yu. Golovkin
I. N. Shanaev
O .V. Zotova
author_facet R. E. Kalinin
E. P. Kulikov
N. I. Verkin
S. A. Mertsalov
E. Yu. Golovkin
I. N. Shanaev
O .V. Zotova
author_sort R. E. Kalinin
collection DOAJ
description Interventional oncology is a rapidly evolving field of cancer treatment. Minimally invasive techniques, such as transarterial embolization with chemotherapeutic and radioactive agents, are common treatments and are found in many guidelines for the treatment of primary and metastatic liver lesions. It is known that the growth and development of a malignant neoplasm is primarily determined by angiogenesis. Rapid growth is ensured where the formation is directly related to the arterial bed. Therefore, when the drug is injected into the target vessel and providing tissue ischemia, it is possible to achieve a high degree of tumor pathomorphosis. This technique has an advantage for patients who, in some cases, cannot be treated surgically, and also increases the effectiveness of the chemotherapeutic effect. With the advent of necessary equipment in hospitals and the accumulation of experience in the use of minimally invasive interventions, it became possible to implement a new method of treating tumors of various localizations. In this review, we consider the results of domestic and foreign authors on the topic of intra-arterial chemoembolization before surgical treatment in patients with rectal cancer. It is noted that the analysis of the literature revealed a small number of works devoted to the chosen topic, despite the relevance of this problem for modern oncology.
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spelling doaj-art-53ccced22db5472296bfde2e20fec6e52025-07-15T11:26:39ZrusRussian Academy of Sciences, Siberian Branch Publishing HouseСибирский научный медицинский журнал2410-25122410-25202024-11-0144561810.18699/SSMJ20240501676Intra-arterial chemoembolization as a component of neoadjuvant treatment of rectal cancer. Literature reviewR. E. Kalinin0E. P. Kulikov1N. I. Verkin2S. A. Mertsalov3E. Yu. Golovkin4I. N. Shanaev5O .V. Zotova6Ryazan State Medical University named after Academician I.P. Pavlov of Minzdrav of RussiaRyazan State Medical University named after Academician I.P. Pavlov of Minzdrav of Russia ; Ryazan Regional Clinical Oncology DispensaryRyazan Regional Clinical Oncology DispensaryRyazan State Medical University named after Academician I.P. Pavlov of Minzdrav of Russia ; Ryazan Regional Clinical Oncology DispensaryRyazan State Medical University named after Academician I.P. Pavlov of Minzdrav of Russia ; Ryazan Regional Clinical Oncology DispensaryRyazan State Medical University named after Academician I.P. Pavlov of Minzdrav of Russia ; Ryazan Regional Clinical Oncology DispensaryRyazan State Medical University named after Academician I.P. Pavlov of Minzdrav of RussiaInterventional oncology is a rapidly evolving field of cancer treatment. Minimally invasive techniques, such as transarterial embolization with chemotherapeutic and radioactive agents, are common treatments and are found in many guidelines for the treatment of primary and metastatic liver lesions. It is known that the growth and development of a malignant neoplasm is primarily determined by angiogenesis. Rapid growth is ensured where the formation is directly related to the arterial bed. Therefore, when the drug is injected into the target vessel and providing tissue ischemia, it is possible to achieve a high degree of tumor pathomorphosis. This technique has an advantage for patients who, in some cases, cannot be treated surgically, and also increases the effectiveness of the chemotherapeutic effect. With the advent of necessary equipment in hospitals and the accumulation of experience in the use of minimally invasive interventions, it became possible to implement a new method of treating tumors of various localizations. In this review, we consider the results of domestic and foreign authors on the topic of intra-arterial chemoembolization before surgical treatment in patients with rectal cancer. It is noted that the analysis of the literature revealed a small number of works devoted to the chosen topic, despite the relevance of this problem for modern oncology.https://sibmed.elpub.ru/jour/article/view/1697colorectal cancerrectal cancerintra-arterial chemoembolizationneoadjuvant therapysurvival
spellingShingle R. E. Kalinin
E. P. Kulikov
N. I. Verkin
S. A. Mertsalov
E. Yu. Golovkin
I. N. Shanaev
O .V. Zotova
Intra-arterial chemoembolization as a component of neoadjuvant treatment of rectal cancer. Literature review
Сибирский научный медицинский журнал
colorectal cancer
rectal cancer
intra-arterial chemoembolization
neoadjuvant therapy
survival
title Intra-arterial chemoembolization as a component of neoadjuvant treatment of rectal cancer. Literature review
title_full Intra-arterial chemoembolization as a component of neoadjuvant treatment of rectal cancer. Literature review
title_fullStr Intra-arterial chemoembolization as a component of neoadjuvant treatment of rectal cancer. Literature review
title_full_unstemmed Intra-arterial chemoembolization as a component of neoadjuvant treatment of rectal cancer. Literature review
title_short Intra-arterial chemoembolization as a component of neoadjuvant treatment of rectal cancer. Literature review
title_sort intra arterial chemoembolization as a component of neoadjuvant treatment of rectal cancer literature review
topic colorectal cancer
rectal cancer
intra-arterial chemoembolization
neoadjuvant therapy
survival
url https://sibmed.elpub.ru/jour/article/view/1697
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