Differentiated approach to rhythm conversion in patients with atrial fibrillation and flutter

The importance of relieving paroxysms of fibrillation and atrial flutter is determined by a huge number of patients suffering from this pathology and its recurrent course.Objective: To create an algorithm for the treatment of patients with atrial fibrillation and atrial flutter by comparing the effi...

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Main Authors: A. G. Pronin, A. V. Prokopenko, D. K. Glukhov
Format: Article
Language:Russian
Published: Private institution educational organization of higher education "Medical University "ReaViz" 2021-12-01
Series:Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
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Online Access:https://vestnik.reaviz.ru/jour/article/view/327
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author A. G. Pronin
A. V. Prokopenko
D. K. Glukhov
author_facet A. G. Pronin
A. V. Prokopenko
D. K. Glukhov
author_sort A. G. Pronin
collection DOAJ
description The importance of relieving paroxysms of fibrillation and atrial flutter is determined by a huge number of patients suffering from this pathology and its recurrent course.Objective: To create an algorithm for the treatment of patients with atrial fibrillation and atrial flutter by comparing the efficacy and safety of drug-induced rhythm conversion with amiodarone, propafenone, procainamide, niferidil and electropulse therapy.Material and methods. Heart rate conversion was performed in 299 patients. Amiodarone was used as a drug for therapy in 93 patients, propafenone in 34, procainamide in 52, and niferidil in 50. 70 patients underwent electropulse therapy. A comparative analysis was carried out to establish the effectiveness and safety of heart rate conversion by these methods.Results. The effectiveness of conversion rhythm in atrial fibrillation with the help of electropulse therapy, propafenone, niferidil, procainamide and amiadarone has been established, which is 90,3%, 82,4%, 77,4%, 72,5% and 70.5%, respectively. It was also found that the use of electro-pulse therapy and niferidil, in which sinus rhythm recovery occurs in 94.4% and 78.9%, respectively, against 58.3% and 26.7% of patients receiving procainamide and amiodarone, respectively, is most appropriate for the relief of atrial flutter. Often, when using niferidil, ventricular extrasystole and prolongation of the QT interval during electrography developed in comparison with patients of other groups. Ventricular tachycardia, including the "pirouette" type, sinoatrial blockade, AV blockade of various degrees, were also slightly more often registered in these patients.Conclusions. In order to stop atrial fibrillation, there are no differences between medications, and it is better to perform rhythm conversion with atrial flutter with niferidil or electro-pulse therapy.
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series Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
spelling doaj-art-5301c56b7bfb4e00b57d209feb9d45012025-08-03T13:33:55ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792021-12-0106425010.20340/vmi-rvz.2021.6.CLIN.1263Differentiated approach to rhythm conversion in patients with atrial fibrillation and flutterA. G. Pronin0A. V. Prokopenko1D. K. Glukhov2Moscow Medical University “Reaviz”; National Medical and Surgical Center named after N.I. PirogovNational Medical and Surgical Center named after N.I. PirogovNational Medical and Surgical Center named after N.I. PirogovThe importance of relieving paroxysms of fibrillation and atrial flutter is determined by a huge number of patients suffering from this pathology and its recurrent course.Objective: To create an algorithm for the treatment of patients with atrial fibrillation and atrial flutter by comparing the efficacy and safety of drug-induced rhythm conversion with amiodarone, propafenone, procainamide, niferidil and electropulse therapy.Material and methods. Heart rate conversion was performed in 299 patients. Amiodarone was used as a drug for therapy in 93 patients, propafenone in 34, procainamide in 52, and niferidil in 50. 70 patients underwent electropulse therapy. A comparative analysis was carried out to establish the effectiveness and safety of heart rate conversion by these methods.Results. The effectiveness of conversion rhythm in atrial fibrillation with the help of electropulse therapy, propafenone, niferidil, procainamide and amiadarone has been established, which is 90,3%, 82,4%, 77,4%, 72,5% and 70.5%, respectively. It was also found that the use of electro-pulse therapy and niferidil, in which sinus rhythm recovery occurs in 94.4% and 78.9%, respectively, against 58.3% and 26.7% of patients receiving procainamide and amiodarone, respectively, is most appropriate for the relief of atrial flutter. Often, when using niferidil, ventricular extrasystole and prolongation of the QT interval during electrography developed in comparison with patients of other groups. Ventricular tachycardia, including the "pirouette" type, sinoatrial blockade, AV blockade of various degrees, were also slightly more often registered in these patients.Conclusions. In order to stop atrial fibrillation, there are no differences between medications, and it is better to perform rhythm conversion with atrial flutter with niferidil or electro-pulse therapy.https://vestnik.reaviz.ru/jour/article/view/327drug conversion of heart rhythmatrial fibrillationatrial flutterniferidil
spellingShingle A. G. Pronin
A. V. Prokopenko
D. K. Glukhov
Differentiated approach to rhythm conversion in patients with atrial fibrillation and flutter
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
drug conversion of heart rhythm
atrial fibrillation
atrial flutter
niferidil
title Differentiated approach to rhythm conversion in patients with atrial fibrillation and flutter
title_full Differentiated approach to rhythm conversion in patients with atrial fibrillation and flutter
title_fullStr Differentiated approach to rhythm conversion in patients with atrial fibrillation and flutter
title_full_unstemmed Differentiated approach to rhythm conversion in patients with atrial fibrillation and flutter
title_short Differentiated approach to rhythm conversion in patients with atrial fibrillation and flutter
title_sort differentiated approach to rhythm conversion in patients with atrial fibrillation and flutter
topic drug conversion of heart rhythm
atrial fibrillation
atrial flutter
niferidil
url https://vestnik.reaviz.ru/jour/article/view/327
work_keys_str_mv AT agpronin differentiatedapproachtorhythmconversioninpatientswithatrialfibrillationandflutter
AT avprokopenko differentiatedapproachtorhythmconversioninpatientswithatrialfibrillationandflutter
AT dkglukhov differentiatedapproachtorhythmconversioninpatientswithatrialfibrillationandflutter