Metastatic mediastinal malignant tumors of gastrointestinal origin with occult primary lesions: a case report

Metastatic mediastinal malignant tumors of gastrointestinal origin with occult primary lesions: a case report

Cancer of unknown primary origin (CUP), accounting for 3–5% of malignancies, poses significant diagnostic challenges because of the absence of identifiable primary lesions. While common occult primary tumors involve the lung or pancreas, gastrointestinal (GI)-originated mediastinal metastases are ex...

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Bibliographic Details
Main Authors: Yaxuan Liu, Liang liang Yang, Wen teng Hu, Rui jiang Lin, Song la Bai, Min jie Ma, Biao Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
cancer of unknown primary
mediastinal metastasis
gastrointestinal immunophenotype
solitary metastasis
diagnostic biomarkers
liquid biopsy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1625668/full
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