HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case Study
Progressive multifocal leukoencephalopathy (PML) is a rare, life-threatening, infectious, lytic, demyelinating disease that results from reactivation of the virulent JC polyomavirus (JCV) “major opportunistic infection” in immunosuppressed individuals. We reported a case of a young girl who present...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2023-07-01
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| Series: | Acta Medica Indonesiana |
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| Online Access: | http://www.actamedindones.org/index.php/ijim/article/view/2336 |
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| author | Elsayed Abed Ahmed Farag El-adawey Mohamed Hamed Rashad Ahmed Essmat Mohammed Ali Ahmed Hassan Elsheshiny Abdel-Ghaffar Fayed Fathy Elbaz Mahmoud Galal Ahmed Zohreh Abna Shaimaa Sayed Khater |
| author_facet | Elsayed Abed Ahmed Farag El-adawey Mohamed Hamed Rashad Ahmed Essmat Mohammed Ali Ahmed Hassan Elsheshiny Abdel-Ghaffar Fayed Fathy Elbaz Mahmoud Galal Ahmed Zohreh Abna Shaimaa Sayed Khater |
| author_sort | Elsayed Abed |
| collection | DOAJ |
| description |
Progressive multifocal leukoencephalopathy (PML) is a rare, life-threatening, infectious, lytic, demyelinating disease that results from reactivation of the virulent JC polyomavirus (JCV) “major opportunistic infection” in immunosuppressed individuals. We reported a case of a young girl who presented with new onset focal neurological defect, evaluated, and laboratory and radiological findings in the context of a clinical setting confirmed HIV-related-PML infection. However, remyelination does not occur, the patients may develop complications in the long term including cognitive impairment, sensory deficits, motor deficits, and disturbances in balance. We must increase our knowledge about HIV- related PML in any patient with reduced immunity and who presented with new onset neurological defect.
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| format | Article |
| id | doaj-art-4fa1b1c832a2429a92d2335e9f94b6b1 |
| institution | Matheson Library |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2023-07-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-4fa1b1c832a2429a92d2335e9f94b6b12025-07-14T07:00:45ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322023-07-01552HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case StudyElsayed Abed0Ahmed Farag El-adawey1Mohamed Hamed Rashad2Ahmed Essmat3Mohammed Ali4Ahmed Hassan Elsheshiny5Abdel-Ghaffar Fayed6Fathy Elbaz7Mahmoud Galal Ahmed8Zohreh Abna9Shaimaa Sayed Khater10Department of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, EgyptDepartment of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, EgyptDepartment of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, EgyptDepartment of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, EgyptDepartment of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, EgyptDepartment of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, EgyptDepartment of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, EgyptDepartment of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, EgyptDepartment of Neurology, Faculty of Medicine, Al-Azhar University, Cairo, 11651, EgyptMS Fellowship, Department of Neurology, Tehran University of Medical Sciences, Tehran, IranDepartment of Neurology, Faculty of Medicine, Ain Shams University, Cairo, 11566, Egypt Progressive multifocal leukoencephalopathy (PML) is a rare, life-threatening, infectious, lytic, demyelinating disease that results from reactivation of the virulent JC polyomavirus (JCV) “major opportunistic infection” in immunosuppressed individuals. We reported a case of a young girl who presented with new onset focal neurological defect, evaluated, and laboratory and radiological findings in the context of a clinical setting confirmed HIV-related-PML infection. However, remyelination does not occur, the patients may develop complications in the long term including cognitive impairment, sensory deficits, motor deficits, and disturbances in balance. We must increase our knowledge about HIV- related PML in any patient with reduced immunity and who presented with new onset neurological defect. http://www.actamedindones.org/index.php/ijim/article/view/2336Progressive multifocalleukoencephalopathyJC virusdemyelinating disease |
| spellingShingle | Elsayed Abed Ahmed Farag El-adawey Mohamed Hamed Rashad Ahmed Essmat Mohammed Ali Ahmed Hassan Elsheshiny Abdel-Ghaffar Fayed Fathy Elbaz Mahmoud Galal Ahmed Zohreh Abna Shaimaa Sayed Khater HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case Study Acta Medica Indonesiana Progressive multifocal leukoencephalopathy JC virus demyelinating disease |
| title | HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case Study |
| title_full | HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case Study |
| title_fullStr | HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case Study |
| title_full_unstemmed | HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case Study |
| title_short | HIV-Associated Progressive Multifocal Leukoencephalopathy: A Case Study |
| title_sort | hiv associated progressive multifocal leukoencephalopathy a case study |
| topic | Progressive multifocal leukoencephalopathy JC virus demyelinating disease |
| url | http://www.actamedindones.org/index.php/ijim/article/view/2336 |
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