Synthesis of two PNA thymine monomers based on L-alanine and glycine
Effective preparative synthesis of two thymine containing monomers of polyamide DNA-mimics based on L-alanine and glycine is presented. The results of investigation are more effective steps for allyl ester protective group incorporation and coupling of thymin-1-yl acetic acid with pseudopeptide inte...
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| Format: | Article |
| Language: | Russian |
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MIREA - Russian Technological University
2010-02-01
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| Series: | Тонкие химические технологии |
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| Online Access: | https://www.finechem-mirea.ru/jour/article/view/1025 |
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| author | M. A. Lyanov Yu. G. Kirillova D. I. Prokhorov A. I. Lyutik O. V. Esipova V. I. Shvets |
| author_facet | M. A. Lyanov Yu. G. Kirillova D. I. Prokhorov A. I. Lyutik O. V. Esipova V. I. Shvets |
| author_sort | M. A. Lyanov |
| collection | DOAJ |
| description | Effective preparative synthesis of two thymine containing monomers of polyamide DNA-mimics based on L-alanine and glycine is presented. The results of investigation are more effective steps for allyl ester protective group incorporation and coupling of thymin-1-yl acetic acid with pseudopeptide intermediate. |
| format | Article |
| id | doaj-art-4f3b2ee4d26d4cd5bcb083b4c6970ee9 |
| institution | Matheson Library |
| issn | 2410-6593 2686-7575 |
| language | Russian |
| publishDate | 2010-02-01 |
| publisher | MIREA - Russian Technological University |
| record_format | Article |
| series | Тонкие химические технологии |
| spelling | doaj-art-4f3b2ee4d26d4cd5bcb083b4c6970ee92025-08-04T10:19:32ZrusMIREA - Russian Technological UniversityТонкие химические технологии2410-65932686-75752010-02-01511041081019Synthesis of two PNA thymine monomers based on L-alanine and glycineM. A. Lyanov0Yu. G. Kirillova1D. I. Prokhorov2A. I. Lyutik3O. V. Esipova4V. I. Shvets5МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86Effective preparative synthesis of two thymine containing monomers of polyamide DNA-mimics based on L-alanine and glycine is presented. The results of investigation are more effective steps for allyl ester protective group incorporation and coupling of thymin-1-yl acetic acid with pseudopeptide intermediate.https://www.finechem-mirea.ru/jour/article/view/1025peptide nucleic acids (pna)chiral monomers of pnapseudopeptidesmitsunobu reaction |
| spellingShingle | M. A. Lyanov Yu. G. Kirillova D. I. Prokhorov A. I. Lyutik O. V. Esipova V. I. Shvets Synthesis of two PNA thymine monomers based on L-alanine and glycine Тонкие химические технологии peptide nucleic acids (pna) chiral monomers of pna pseudopeptides mitsunobu reaction |
| title | Synthesis of two PNA thymine monomers based on L-alanine and glycine |
| title_full | Synthesis of two PNA thymine monomers based on L-alanine and glycine |
| title_fullStr | Synthesis of two PNA thymine monomers based on L-alanine and glycine |
| title_full_unstemmed | Synthesis of two PNA thymine monomers based on L-alanine and glycine |
| title_short | Synthesis of two PNA thymine monomers based on L-alanine and glycine |
| title_sort | synthesis of two pna thymine monomers based on l alanine and glycine |
| topic | peptide nucleic acids (pna) chiral monomers of pna pseudopeptides mitsunobu reaction |
| url | https://www.finechem-mirea.ru/jour/article/view/1025 |
| work_keys_str_mv | AT malyanov synthesisoftwopnathyminemonomersbasedonlalanineandglycine AT yugkirillova synthesisoftwopnathyminemonomersbasedonlalanineandglycine AT diprokhorov synthesisoftwopnathyminemonomersbasedonlalanineandglycine AT ailyutik synthesisoftwopnathyminemonomersbasedonlalanineandglycine AT ovesipova synthesisoftwopnathyminemonomersbasedonlalanineandglycine AT vishvets synthesisoftwopnathyminemonomersbasedonlalanineandglycine |