Identification and Validation of Circadian Rhythm‐Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning

Identification and Validation of Circadian Rhythm‐Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning

ABSTRACT Background Low back pain is a significant burden worldwide, and intervertebral disc degeneration (IVDD) is identified as the primary cause. Recent research has emphasized the significant role of circadian rhythms (CRs) and immunity in affecting intervertebral discs (IVD). However, the influ...

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Bibliographic Details
Main Authors: Yongbo Zhang, Liuyang Chen, Sheng Yang, Rui Dai, Hua Sun, Liang Zhang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:JOR Spine
Subjects:
bioinformatics
circadian rhythms
immune cell infiltration
intervertebral disc degeneration
machine learning algorithms
mesenchymal stem cell
Online Access:https://doi.org/10.1002/jsp2.70066
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https://doi.org/10.1002/jsp2.70066

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