Alanine-substituted mutant on Gly373 and Asn375 of Cry1Ai-h-loop 2 causes reduction in both toxicity and binding against Helicoverpa armigera
Cry1Ai-h-loop 2 is a mutant of Cry1Ai constructed by exchanging loop 2 from Cry1Ah protein and shows insecticidal activity against Helicoverpa armigera. The toxicity of Cry1Ai-h-loop 2, in contrast to the very low toxicity of Cry1Ai, is closely associated with the eleven residues in the loop 2 regio...
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Main Authors: | Yu-xiao LIU, Zi-shan ZHOU, Ge-mei LIANG, Fu-ping SONG, Jie ZHANG |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2019-05-01
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Series: | Journal of Integrative Agriculture |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2095311918619331 |
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