Chinese massage therapy (Tuina) inhibits motor neuron apoptosis in rats with sciatic nerve injury by regulating the cPLA2 and RhoA/ROCK2 signaling pathways

Chinese massage therapy (Tuina) inhibits motor neuron apoptosis in rats with sciatic nerve injury by regulating the cPLA2 and RhoA/ROCK2 signaling pathways

ObjectiveTo investigate whether Tuina therapy alleviated inflammation and motor neuron apoptosis in sciatic nerve injury (SNI) rats by regulating cytosolic phospholipase A2 (cPLA2) and Ras homolog family member A/Rho-associated coiled-coil comprising protein kinase 2 (RhoA/ROCK2) signaling cascades....

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Bibliographic Details
Main Authors: Jiawei Sun, Yingqi Zhang, Zhifeng Liu, Hanyu Zhang, Jiayue Liu, Yue Xu, Rentuya Na, Hongzheng Zhang, Jiawang Yan, Tianyuan Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Neurology
Subjects:
peripheral nerve injury
Tuina
apoptosis
inflammatory response
CPLA2
RhoA/ROCK2 pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1622602/full
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