Surgical and Oncological Outcomes of Minimally Invasive Left Pancreatectomy for Pancreatic Cancer: Robotic vs. Laparoscopic Approach
Objective: This study compares the surgical and oncological outcomes of minimally invasive robotic (RLP) and laparoscopic (LLP) left pancreatectomy in pancreatic cancer (PC) patients. Methods: Data from patients who underwent minimally invasive left pancreatectomy between 2013 and 2023 were analyzed...
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| Language: | English |
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MDPI AG
2025-06-01
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| Series: | Current Oncology |
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| Online Access: | https://www.mdpi.com/1718-7729/32/7/376 |
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| author | Matteo De Pastena Gabriella Lionetto Salvatore Paiella Martina Maruccio Federico Faustini Elisa Venturini Antonio Pea Fabio Casciani Giuseppe Malleo Alessandro Esposito |
| author_facet | Matteo De Pastena Gabriella Lionetto Salvatore Paiella Martina Maruccio Federico Faustini Elisa Venturini Antonio Pea Fabio Casciani Giuseppe Malleo Alessandro Esposito |
| author_sort | Matteo De Pastena |
| collection | DOAJ |
| description | Objective: This study compares the surgical and oncological outcomes of minimally invasive robotic (RLP) and laparoscopic (LLP) left pancreatectomy in pancreatic cancer (PC) patients. Methods: Data from patients who underwent minimally invasive left pancreatectomy between 2013 and 2023 were analyzed. Two groups were identified: RLP and LLP. Perioperative outcomes were compared, including operative time, blood loss, conversion rate, and postoperative complications. Oncological outcomes included margin status, lymph node retrieval, lymph node status, overall survival (OS), and disease-free survival (DFS). Results: Fifty-four patients were divided into the LLP (<i>n</i> = 39) and RLP (<i>n</i> = 15) groups. The median operative time was shorter for LLP than RLP [260 min vs. 366 min, <i>p</i> = 0.007]. Blood loss and conversion rates were comparable (<i>p</i> > 0.05). In the LLP group, significantly more lymph nodes were harvested (29 vs. 19, <i>p</i> = 0.05), and a higher percentage of positive lymph nodes was noted (72% vs. 40%, <i>p</i> = 0.033). No significant difference was found in the R0 resection status (82% vs. 73%, <i>p</i> = 0.358). After a median follow-up of 26 months, OS (23 months vs. 34 months, <i>p</i> = 0.812) and DFS (17 months vs. 16 months, <i>p</i> = 0.635) were similar. Conclusion: RLP provides outcomes identical to LLP in treating body–tail pancreatic cancer, with further studies needed to confirm its long-term oncological efficacy. |
| format | Article |
| id | doaj-art-4bc69ade1cb04eb9a05a68bcc64c29b6 |
| institution | Matheson Library |
| issn | 1198-0052 1718-7729 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj-art-4bc69ade1cb04eb9a05a68bcc64c29b62025-07-25T13:19:21ZengMDPI AGCurrent Oncology1198-00521718-77292025-06-0132737610.3390/curroncol32070376Surgical and Oncological Outcomes of Minimally Invasive Left Pancreatectomy for Pancreatic Cancer: Robotic vs. Laparoscopic ApproachMatteo De Pastena0Gabriella Lionetto1Salvatore Paiella2Martina Maruccio3Federico Faustini4Elisa Venturini5Antonio Pea6Fabio Casciani7Giuseppe Malleo8Alessandro Esposito9Pancreatic Surgery Unit, University of Verona Hospital Trust, 37129 Verona, ItalyUniversity of Verona, 37129 Verona, ItalyUniversity of Verona, 37129 Verona, ItalyPancreatic Surgery Unit, University of Verona Hospital Trust, 37129 Verona, ItalyPancreatic Surgery Unit, University of Verona Hospital Trust, 37129 Verona, ItalyUniversity of Verona, 37129 Verona, ItalyUniversity of Verona, 37129 Verona, ItalyPancreatic Surgery Unit, University of Verona Hospital Trust, 37129 Verona, ItalyUniversity of Verona, 37129 Verona, ItalyPancreatic Surgery Unit, University of Verona Hospital Trust, 37129 Verona, ItalyObjective: This study compares the surgical and oncological outcomes of minimally invasive robotic (RLP) and laparoscopic (LLP) left pancreatectomy in pancreatic cancer (PC) patients. Methods: Data from patients who underwent minimally invasive left pancreatectomy between 2013 and 2023 were analyzed. Two groups were identified: RLP and LLP. Perioperative outcomes were compared, including operative time, blood loss, conversion rate, and postoperative complications. Oncological outcomes included margin status, lymph node retrieval, lymph node status, overall survival (OS), and disease-free survival (DFS). Results: Fifty-four patients were divided into the LLP (<i>n</i> = 39) and RLP (<i>n</i> = 15) groups. The median operative time was shorter for LLP than RLP [260 min vs. 366 min, <i>p</i> = 0.007]. Blood loss and conversion rates were comparable (<i>p</i> > 0.05). In the LLP group, significantly more lymph nodes were harvested (29 vs. 19, <i>p</i> = 0.05), and a higher percentage of positive lymph nodes was noted (72% vs. 40%, <i>p</i> = 0.033). No significant difference was found in the R0 resection status (82% vs. 73%, <i>p</i> = 0.358). After a median follow-up of 26 months, OS (23 months vs. 34 months, <i>p</i> = 0.812) and DFS (17 months vs. 16 months, <i>p</i> = 0.635) were similar. Conclusion: RLP provides outcomes identical to LLP in treating body–tail pancreatic cancer, with further studies needed to confirm its long-term oncological efficacy.https://www.mdpi.com/1718-7729/32/7/376ductal adenocarcinomadistal pancreatectomyrobotic distal pancreatectomylaparoscopic distal pancreatectomyprognosissurvival |
| spellingShingle | Matteo De Pastena Gabriella Lionetto Salvatore Paiella Martina Maruccio Federico Faustini Elisa Venturini Antonio Pea Fabio Casciani Giuseppe Malleo Alessandro Esposito Surgical and Oncological Outcomes of Minimally Invasive Left Pancreatectomy for Pancreatic Cancer: Robotic vs. Laparoscopic Approach Current Oncology ductal adenocarcinoma distal pancreatectomy robotic distal pancreatectomy laparoscopic distal pancreatectomy prognosis survival |
| title | Surgical and Oncological Outcomes of Minimally Invasive Left Pancreatectomy for Pancreatic Cancer: Robotic vs. Laparoscopic Approach |
| title_full | Surgical and Oncological Outcomes of Minimally Invasive Left Pancreatectomy for Pancreatic Cancer: Robotic vs. Laparoscopic Approach |
| title_fullStr | Surgical and Oncological Outcomes of Minimally Invasive Left Pancreatectomy for Pancreatic Cancer: Robotic vs. Laparoscopic Approach |
| title_full_unstemmed | Surgical and Oncological Outcomes of Minimally Invasive Left Pancreatectomy for Pancreatic Cancer: Robotic vs. Laparoscopic Approach |
| title_short | Surgical and Oncological Outcomes of Minimally Invasive Left Pancreatectomy for Pancreatic Cancer: Robotic vs. Laparoscopic Approach |
| title_sort | surgical and oncological outcomes of minimally invasive left pancreatectomy for pancreatic cancer robotic vs laparoscopic approach |
| topic | ductal adenocarcinoma distal pancreatectomy robotic distal pancreatectomy laparoscopic distal pancreatectomy prognosis survival |
| url | https://www.mdpi.com/1718-7729/32/7/376 |
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