Genes copy number variation in colorectal cancer patients as a marker of the disease clinical outcome and response to therapy
Abnormal gene copies, a special type of genetic polymorphism, is a hallmark of most solid tumors, including colorectal cancer. Abnormal copy number of genes leads to tumor-specific genomic imbalance, which manifests itself already in precancerous precursor lesions. The aim of this review was to syst...
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Main Authors: | A. A. Maslov, L. Kh. Chalkhakhyan, S. A. Malinin, G. V. Kaminsky, E. A. Mirzoyan |
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Format: | Article |
Language: | Russian |
Published: |
ANO "Perspective of oncology"
2022-06-01
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Series: | Южно-Российский онкологический журнал |
Subjects: | |
Online Access: | https://www.cancersp.com/jour/article/view/161 |
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