Mechanochemistry: Fundamental Principles and Applications

Abstract Mechanochemistry is an emerging research field at the interface of physics, mechanics, materials science, and chemistry. Complementary to traditional activation methods in chemistry, such as heat, electricity, and light, mechanochemistry focuses on the activation of chemical reactions by di...

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Main Authors: Liang Dong, Luofei Li, Huiyan Chen, Yi Cao, Hai Lei
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202403949
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author Liang Dong
Luofei Li
Huiyan Chen
Yi Cao
Hai Lei
author_facet Liang Dong
Luofei Li
Huiyan Chen
Yi Cao
Hai Lei
author_sort Liang Dong
collection DOAJ
description Abstract Mechanochemistry is an emerging research field at the interface of physics, mechanics, materials science, and chemistry. Complementary to traditional activation methods in chemistry, such as heat, electricity, and light, mechanochemistry focuses on the activation of chemical reactions by directly or indirectly applying mechanical forces. It has evolved as a powerful tool for controlling chemical reactions in solid state systems, sensing and responding to stresses in polymer materials, regulating interfacial adhesions, and stimulating biological processes. By combining theoretical approaches, simulations and experimental techniques, researchers have gained intricate insights into the mechanisms underlying mechanochemistry. In this review, the physical chemistry principles underpinning mechanochemistry are elucidated and a comprehensive overview of recent significant achievements in the discovery of mechanically responsive chemical processes is provided, with a particular emphasis on their applications in materials science. Additionally, The perspectives and insights into potential future directions for this exciting research field are offered.
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spelling doaj-art-4b8e0980bbef4ea088e4e373b60d89c92025-06-26T13:37:17ZengWileyAdvanced Science2198-38442025-06-011224n/an/a10.1002/advs.202403949Mechanochemistry: Fundamental Principles and ApplicationsLiang Dong0Luofei Li1Huiyan Chen2Yi Cao3Hai Lei4Collaborative Innovation Center of Advanced Microstructures National Laboratory of Solid State Microstructure Department of Physics Nanjing University Nanjing Jiangsu 210093 P. R. ChinaCollaborative Innovation Center of Advanced Microstructures National Laboratory of Solid State Microstructure Department of Physics Nanjing University Nanjing Jiangsu 210093 P. R. ChinaCollaborative Innovation Center of Advanced Microstructures National Laboratory of Solid State Microstructure Department of Physics Nanjing University Nanjing Jiangsu 210093 P. R. ChinaCollaborative Innovation Center of Advanced Microstructures National Laboratory of Solid State Microstructure Department of Physics Nanjing University Nanjing Jiangsu 210093 P. R. ChinaSchool of Physics Zhejiang University Hangzhou Zhejiang 310027 P. R. ChinaAbstract Mechanochemistry is an emerging research field at the interface of physics, mechanics, materials science, and chemistry. Complementary to traditional activation methods in chemistry, such as heat, electricity, and light, mechanochemistry focuses on the activation of chemical reactions by directly or indirectly applying mechanical forces. It has evolved as a powerful tool for controlling chemical reactions in solid state systems, sensing and responding to stresses in polymer materials, regulating interfacial adhesions, and stimulating biological processes. By combining theoretical approaches, simulations and experimental techniques, researchers have gained intricate insights into the mechanisms underlying mechanochemistry. In this review, the physical chemistry principles underpinning mechanochemistry are elucidated and a comprehensive overview of recent significant achievements in the discovery of mechanically responsive chemical processes is provided, with a particular emphasis on their applications in materials science. Additionally, The perspectives and insights into potential future directions for this exciting research field are offered.https://doi.org/10.1002/advs.202403949biomechanochemistryforcemechanismmechanochemistrysingle moleculesoft materials
spellingShingle Liang Dong
Luofei Li
Huiyan Chen
Yi Cao
Hai Lei
Mechanochemistry: Fundamental Principles and Applications
Advanced Science
biomechanochemistry
force
mechanism
mechanochemistry
single molecule
soft materials
title Mechanochemistry: Fundamental Principles and Applications
title_full Mechanochemistry: Fundamental Principles and Applications
title_fullStr Mechanochemistry: Fundamental Principles and Applications
title_full_unstemmed Mechanochemistry: Fundamental Principles and Applications
title_short Mechanochemistry: Fundamental Principles and Applications
title_sort mechanochemistry fundamental principles and applications
topic biomechanochemistry
force
mechanism
mechanochemistry
single molecule
soft materials
url https://doi.org/10.1002/advs.202403949
work_keys_str_mv AT liangdong mechanochemistryfundamentalprinciplesandapplications
AT luofeili mechanochemistryfundamentalprinciplesandapplications
AT huiyanchen mechanochemistryfundamentalprinciplesandapplications
AT yicao mechanochemistryfundamentalprinciplesandapplications
AT hailei mechanochemistryfundamentalprinciplesandapplications