Harmine-mediated Reduction of Bone Cancer Pain in Rats Correlates With Suppressed DYRK1A/NF-κB Signaling Axis

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Harmine-mediated Reduction of Bone Cancer Pain in Rats Correlates With Suppressed DYRK1A/NF-κB Signaling Axis

Background: Bone cancer pain (BCP) is a prevalent chronic pain condition and a common clinical symptom in patients with advanced cancer. It significantly affects the mobility and quality of life of patients; however, current treatments offer limited efficacy. Harmine, a beta-carbo...

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Bibliographic Details
Main Authors:	Shuyao Zhang, Shang Zheng, Jia Jin, Yuhua Li, Liping Chen, Junjie Lin, Ming Yao, Longsheng Xu
Format:	Article
Language:	English
Published:	IMR Press 2025-06-01
Series:	Journal of Integrative Neuroscience
Subjects:	bone cancer pain harmine dyrk1a/nf-κb signaling pathway spinal cord dorsal horn
Online Access:	https://www.imrpress.com/journal/JIN/24/6/10.31083/JIN38100
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