PERIPHERAL BLOOD MONONUCLEAR DNA DAMAGE IDENTIFIED BY THE «СOMET» METHOD, AS A POSSIBLE INDICATOR OF SENSITIVITY OF MELANOMA TO IMMUNOTHERAPY WITH NIVOLUMAB

PERIPHERAL BLOOD MONONUCLEAR DNA DAMAGE IDENTIFIED BY THE «СOMET» METHOD, AS A POSSIBLE INDICATOR OF SENSITIVITY OF MELANOMA TO IMMUNOTHERAPY WITH NIVOLUMAB

Purpose of the study: to assess whether the determination of the grade of dNA damage in the blood lymphocytes of patients with metastatic melanoma can be a criterion for assessing the effectiveness of therapy. Material and Methods. The grade of dNA damage in blood mononuclear cells was studied using...

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Bibliographic Details
Main Authors: E. V. Tsyrlina, T. E. Poroshina, A. P. Oganesyan, S. A. Protsenko, L. M. Bershtein
Format: Article
Language:Russian
Published: Russian Academy of Sciences, Tomsk National Research Medical Center 2021-05-01
Series:Сибирский онкологический журнал
Subjects:
melanoma
dna damage
mononuclears
«comet» method
nivolumab
Online Access:https://www.siboncoj.ru/jour/article/view/1753
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