Characterisation and In Vitro Drug Release Profiles of Oleanolic Acid- and Asiatic Acid-Loaded Solid Lipid Nanoparticles (SLNs) for Oral Administration

Characterisation and In Vitro Drug Release Profiles of Oleanolic Acid- and Asiatic Acid-Loaded Solid Lipid Nanoparticles (SLNs) for Oral Administration

<b>Objectives:</b> This study characterised and evaluated the stability, solubility, and in vitro drug release of OA- and AA-loaded SLNs. <b>Methods:</b> The OA- and AA-SLNs were formulated using the emulsion solvent evaporation method and characterised based on particle size...

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Bibliographic Details
Main Authors: Michael Oboh, Eman Elhassan, Neil Anthony Koorbanally, Laurencia Govender, Muthulisi Siwela, Thirumala Govender, Blessing Nkazimulo Mkhwanazi
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Pharmaceutics
Subjects:
asiatic acid
drug release
oleanolic acid
oral administration
solid lipid nanoparticles
solubility
Online Access:https://www.mdpi.com/1999-4923/17/6/723
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