ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS
Tonsillopharyngitis is a common multietiological infectious disease, more often caused by streptococci infection. The development and adoption of oral III generation cephalosporins into clinical practice significantly widened the possibilities of treatment of inflammatoryinfectious diseases, includi...
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"Paediatrician" Publishers LLC
2012-03-01
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Series: | Вопросы современной педиатрии |
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Online Access: | https://vsp.spr-journal.ru/jour/article/view/135 |
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author | S. A Karpishchenko E. B. Katinas N. A. Shumilova |
author_facet | S. A Karpishchenko E. B. Katinas N. A. Shumilova |
author_sort | S. A Karpishchenko |
collection | DOAJ |
description | Tonsillopharyngitis is a common multietiological infectious disease, more often caused by streptococci infection. The development and adoption of oral III generation cephalosporins into clinical practice significantly widened the possibilities of treatment of inflammatoryinfectious diseases, including tonsillopharyngitis. One of the III generation cephalosporins is Ceftibuten (Cedax) — a drug with b-lactam properties, which inhibits bacterial peptidoglycan synthesis. It has relatively long post-antibiotic effect, characterized by high activity in point of majority of enterobacteria, and is very stable to destructive action of -lactamases. It also can be accumulated in tissues, providing high concentration of active substance in inflammation nidus. The therapeutic dose of the drug for adults is 400 mg/day. Ceftibuten is recommended and effectively used in pediatric practice in treatment of tonsillopharyngitis and otitis. |
format | Article |
id | doaj-art-47b032bf9c3342b3a08c743e57e5c29c |
institution | Matheson Library |
issn | 1682-5527 1682-5535 |
language | English |
publishDate | 2012-03-01 |
publisher | "Paediatrician" Publishers LLC |
record_format | Article |
series | Вопросы современной педиатрии |
spelling | doaj-art-47b032bf9c3342b3a08c743e57e5c29c2025-08-04T13:09:27Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352012-03-0111214615010.15690/vsp.v11i2.228135ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITISS. A Karpishchenko0E. B. Katinas1N. A. Shumilova2St. Petersburg State I.P. Pavlov Medical UniversitySt. Petersburg State I.P. Pavlov Medical UniversitySt. Petersburg State I.P. Pavlov Medical UniversityTonsillopharyngitis is a common multietiological infectious disease, more often caused by streptococci infection. The development and adoption of oral III generation cephalosporins into clinical practice significantly widened the possibilities of treatment of inflammatoryinfectious diseases, including tonsillopharyngitis. One of the III generation cephalosporins is Ceftibuten (Cedax) — a drug with b-lactam properties, which inhibits bacterial peptidoglycan synthesis. It has relatively long post-antibiotic effect, characterized by high activity in point of majority of enterobacteria, and is very stable to destructive action of -lactamases. It also can be accumulated in tissues, providing high concentration of active substance in inflammation nidus. The therapeutic dose of the drug for adults is 400 mg/day. Ceftibuten is recommended and effectively used in pediatric practice in treatment of tonsillopharyngitis and otitis.https://vsp.spr-journal.ru/jour/article/view/135: ceftibuteniii generation cephalosporinesotitistonsillopharyngitisstreptococcusβ -lactam antibiotics |
spellingShingle | S. A Karpishchenko E. B. Katinas N. A. Shumilova ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS Вопросы современной педиатрии : ceftibuten iii generation cephalosporines otitis tonsillopharyngitis streptococcus β -lactam antibiotics |
title | ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS |
title_full | ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS |
title_fullStr | ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS |
title_full_unstemmed | ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS |
title_short | ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS |
title_sort | oral iii generation cephalosporin ceftibuten in treatment of acute tonsillopharyngitis and otitis |
topic | : ceftibuten iii generation cephalosporines otitis tonsillopharyngitis streptococcus β -lactam antibiotics |
url | https://vsp.spr-journal.ru/jour/article/view/135 |
work_keys_str_mv | AT sakarpishchenko oraliiigenerationcephalosporinceftibutenintreatmentofacutetonsillopharyngitisandotitis AT ebkatinas oraliiigenerationcephalosporinceftibutenintreatmentofacutetonsillopharyngitisandotitis AT nashumilova oraliiigenerationcephalosporinceftibutenintreatmentofacutetonsillopharyngitisandotitis |