ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS

Tonsillopharyngitis is a common multietiological infectious disease, more often caused by streptococci infection. The development and adoption of oral III generation cephalosporins into clinical practice significantly widened the possibilities of treatment of inflammatoryinfectious diseases, includi...

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Main Authors: S. A Karpishchenko, E. B. Katinas, N. A. Shumilova
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2012-03-01
Series:Вопросы современной педиатрии
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Online Access:https://vsp.spr-journal.ru/jour/article/view/135
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author S. A Karpishchenko
E. B. Katinas
N. A. Shumilova
author_facet S. A Karpishchenko
E. B. Katinas
N. A. Shumilova
author_sort S. A Karpishchenko
collection DOAJ
description Tonsillopharyngitis is a common multietiological infectious disease, more often caused by streptococci infection. The development and adoption of oral III generation cephalosporins into clinical practice significantly widened the possibilities of treatment of inflammatoryinfectious diseases, including tonsillopharyngitis. One of the III generation cephalosporins is Ceftibuten (Cedax) — a drug with b-lactam properties, which inhibits bacterial peptidoglycan synthesis. It has relatively long post-antibiotic effect, characterized by high activity in point of majority of enterobacteria, and is very stable to destructive action of -lactamases. It also can be accumulated in tissues, providing high concentration of active substance in inflammation nidus. The therapeutic dose of the drug for adults is 400 mg/day. Ceftibuten is recommended and effectively used in pediatric practice in treatment of tonsillopharyngitis and otitis.
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1682-5535
language English
publishDate 2012-03-01
publisher "Paediatrician" Publishers LLC
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series Вопросы современной педиатрии
spelling doaj-art-47b032bf9c3342b3a08c743e57e5c29c2025-08-04T13:09:27Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352012-03-0111214615010.15690/vsp.v11i2.228135ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITISS. A Karpishchenko0E. B. Katinas1N. A. Shumilova2St. Petersburg State I.P. Pavlov Medical UniversitySt. Petersburg State I.P. Pavlov Medical UniversitySt. Petersburg State I.P. Pavlov Medical UniversityTonsillopharyngitis is a common multietiological infectious disease, more often caused by streptococci infection. The development and adoption of oral III generation cephalosporins into clinical practice significantly widened the possibilities of treatment of inflammatoryinfectious diseases, including tonsillopharyngitis. One of the III generation cephalosporins is Ceftibuten (Cedax) — a drug with b-lactam properties, which inhibits bacterial peptidoglycan synthesis. It has relatively long post-antibiotic effect, characterized by high activity in point of majority of enterobacteria, and is very stable to destructive action of -lactamases. It also can be accumulated in tissues, providing high concentration of active substance in inflammation nidus. The therapeutic dose of the drug for adults is 400 mg/day. Ceftibuten is recommended and effectively used in pediatric practice in treatment of tonsillopharyngitis and otitis.https://vsp.spr-journal.ru/jour/article/view/135: ceftibuteniii generation cephalosporinesotitistonsillopharyngitisstreptococcusβ -lactam antibiotics
spellingShingle S. A Karpishchenko
E. B. Katinas
N. A. Shumilova
ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS
Вопросы современной педиатрии
: ceftibuten
iii generation cephalosporines
otitis
tonsillopharyngitis
streptococcus
β -lactam antibiotics
title ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS
title_full ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS
title_fullStr ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS
title_full_unstemmed ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS
title_short ORAL III GENERATION CEPHALOSPORIN CEFTIBUTEN IN TREATMENT OF ACUTE TONSILLOPHARYNGITIS AND OTITIS
title_sort oral iii generation cephalosporin ceftibuten in treatment of acute tonsillopharyngitis and otitis
topic : ceftibuten
iii generation cephalosporines
otitis
tonsillopharyngitis
streptococcus
β -lactam antibiotics
url https://vsp.spr-journal.ru/jour/article/view/135
work_keys_str_mv AT sakarpishchenko oraliiigenerationcephalosporinceftibutenintreatmentofacutetonsillopharyngitisandotitis
AT ebkatinas oraliiigenerationcephalosporinceftibutenintreatmentofacutetonsillopharyngitisandotitis
AT nashumilova oraliiigenerationcephalosporinceftibutenintreatmentofacutetonsillopharyngitisandotitis