Linking TLR-7 Signaling to Downregulation of Placental P-Glycoprotein: Implications for Fetal Drug Exposure

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Linking TLR-7 Signaling to Downregulation of Placental P-Glycoprotein: Implications for Fetal Drug Exposure

<b>Background/Objectives:</b> Activation of the Toll-like receptor 7 (TLR-7) plays an important role in the pathogenesis of many autoimmune diseases and viral infections. Although we have previously observed inflammation-mediated dysregulation of placental transporters, the role of TLR-7...

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Main Authors:	Mario Riera-Romo, Eliza R McColl, Micheline Piquette-Miller
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Pharmaceutics
Subjects:	viral infections autoimmune diseases TLR-7 inflammation transporters P-glycoprotein
Online Access:	https://www.mdpi.com/1999-4923/17/6/741
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