Analysis of mitochondrial-targeted antioxidant SkQ1 effectiveness on myocardial ischemia-reperfusion injury in a rat model: Focus on morphological and ultrastructural tissue study

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Analysis of mitochondrial-targeted antioxidant SkQ1 effectiveness on myocardial ischemia-reperfusion injury in a rat model: Focus on morphological and ultrastructural tissue study

Mitochondrial-targeted antioxidant SkQ1 demonstrates a high efficiency in animal models and potentially can be used for minimizing postoperative complications in an on-pump open-heart surgery.The aim of study was to the assessment of preservation degree and changes in the isolated rat heart characte...

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Bibliographic Details
Main Authors:	E. A. Senokosova, E. A. Velikanova, R. A. Mukhamadiyarov, O. D. Sidorova, E. O. Krivkina, L. V. Antonova, E. V. Grigoriev
Format:	Article
Language:	Russian
Published:	Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute 2025-03-01
Series:	Фармация и фармакология (Пятигорск)
Subjects:	plastomitin skq1 isolated rat heart oxidative stress ischemia-reperfusion injury langendorff perfusion histology scanning electron microscopy immunofluorescence
Online Access:	https://www.pharmpharm.ru/jour/article/view/1611
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